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Articles Published Processes
6/7/2023 6:39:13 AM | Browse: 207 | Download: 445
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Received |
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2023-01-25 15:50 |
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Peer-Review Started |
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2023-01-25 15:54 |
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To Make the First Decision |
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Return for Revision |
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2023-03-15 03:41 |
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Revised |
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2023-03-23 10:34 |
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Second Decision |
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2023-05-04 03:13 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-05-04 23:19 |
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Articles in Press |
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2023-05-04 23:19 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2023-05-08 20:54 |
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Typeset the Manuscript |
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2023-05-25 06:11 |
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Publish the Manuscript Online |
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2023-06-07 06:39 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Infectious Diseases |
| Manuscript Type |
Review |
| Article Title |
Overview of current detection methods and microRNA potential in Clostridium difficile infection screening
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Marco Bocchetti, Maria Grazia Ferraro, Federica Melisi, Piera Grisolia, Marianna Scrima, Alessia Maria Cossu and Tung On Yau |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Tung On Yau, BSc, MSc, PhD, Instructor, Lecturer, Researcher, School of Science and Technology, Nottingham Trent University, Clifton Lane, Clifton, Nottingham NG11 8NS, United Kingdom. payton.yau@ntu.ac.uk |
| Key Words |
Clostridioides difficile; microRNA; Diagnostic; Prognostic; Biomarker |
| Core Tip |
Clostridioides difficile (C. difficile) infection (CDI) is listed as an urgent threat and early detection and appropriate disease management from hospital-acquired or community-acquired CDI appear to be essential. Currently, stool-based non-invasive screening is the first-line approach to CDI diagnosis, but the accuracy is varied due to different clinical microbiology detection methods; therefore, improving reliability is clearly required. This review summarizes the life cycle and toxicity of C. difficile and examines existing diagnostic potentials on microRNA as novel biomarkers. miRNAs can be easily detected through non-invasive liquid biopsy and can also yield crucial information about ongoing pathological phenomena, particularly in CDI. |
| Publish Date |
2023-06-07 06:39 |
| Citation |
Bocchetti M, Ferraro MG, Melisi F, Grisolia P, Scrima M, Cossu AM, Yau TO. Overview of current detection methods and microRNA potential in Clostridium difficile infection screening. World J Gastroenterol 2023; 29(22): 3385-3399 |
| URL |
https://www.wjgnet.com/1007-9327/full/v29/i22/3385.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v29.i22.3385 |
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