Publication Name	World Journal of Clinical Oncology
Manuscript ID	8348
Country	United States

Received	2013-12-26 13:53
Peer-Review Started	2013-12-26 15:14
To Make the First Decision	2014-03-12 17:05
Return for Revision	2014-03-21 20:23
Revised	2014-04-21 23:09
Second Decision	2014-05-16 17:27
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-05-16 17:48
Articles in Press	2014-05-23 09:09
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-07-24 14:19
Publish the Manuscript Online	2014-08-01 16:16

ISSN	2218-4333 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Topic Highlights
Article Title	Clinical and scientific impact of human papillomavirus on head and neck cancer
Manuscript Source	Invited Manuscript
All Author List	Jeffrey M Friedman, Mark J Stavas and Anthony J Cmelak
Funding Agency and Grant Number
Corresponding Author	Anthony J Cmelak, MD, Professor of Medicine, Department of Radiation Oncology, Vanderbilt University Medical Center, Preston Research Building, B-1003, Nashville, TN 37232-5671, United States. anthony.cmelak@vanderbilt.edu
Key Words	Human papilloma virus; Head and neck cancer; Squamous cell carcinoma; Chemotherapy; Radiation; Molecular biology
Core Tip	Head and neck squamous cell carcinoma (HNSCC) is the fifth most common cancer, and historically, in the developed world, was associated with tobacco and alcohol. However, beginning in 1983, investigators have found a growing proportion of HNSCC patients with human papillomavirus-positive (HPV) tumors who neither drank nor used tobacco. HPV has shifted the epidemiology and prognosis of HNSCC and HPV status is the strongest positive prognostic marker in patients with oropharyngeal SCC. This review will highlight the epidemiological, clinical and molecular discoveries surrounding HPV-related HNSCC over the recent decades and how these findings will guide future treatment approaches.
Publish Date	2014-08-01 16:16
Citation	Friedman JM, Stavas MJ, Cmelak AJ. Clinical and scientific impact of human papillomavirus on head and neck cancer. World J Clin Oncol 2014; 5(4): 781-791
URL	http://www.wjgnet.com/2218-4333/full/v5/i4/781.htm
DOI	http://dx.doi.org/10.5306/wjco.v5.i4.781

Full Article (PDF)	WJCO-5-781.pdf
Full Article (Word)	WJCO-5-781.doc
Manuscript File	8348-Review.docx
Answering Reviewers	8348-Answering reviewers.pdf
Copyright License Agreement	8348-Copyright assignment.pdf
Peer-review Report	8348-Peer review(s).pdf
Scientific Editor Work List	8348-Scientific editor work list.pdf