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Articles Published Processes
6/30/2023 12:54:07 PM | Browse: 313 | Download: 810
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Received |
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2023-02-18 16:32 |
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Peer-Review Started |
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2023-02-18 16:34 |
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To Make the First Decision |
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Return for Revision |
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2023-05-16 13:42 |
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Revised |
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2023-05-25 12:18 |
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Second Decision |
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2023-06-05 03:04 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-06-06 00:54 |
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Articles in Press |
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2023-06-06 00:54 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-06-08 06:20 |
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Publish the Manuscript Online |
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2023-06-30 12:54 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Report |
| Article Title |
Hypothetical hypoxia-driven rapid disease progression in hepatocellular carcinoma post transarterial chemoembolization: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Kai-Fuan Yeo, Amy Ker, Pei-En Kao and Chi-Chih Wang |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Chi-Chih Wang, PhD, Assistant Professor, Director, Director, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Chung Shan Medical University Hospital, No.110 Sec.1, Jianguo N. Rd., Taichung 402306, Taiwan. bananaudwang@gmail.com |
| Key Words |
Carcinoma; hepatocellular; Transarterial chemoembolization; Tumor hypoxia; Disease progression; Tumor burden; Case report |
| Core Tip |
We report an hepatocellular carcinoma (HCC) case with a large tumor burden and infiltrative tumor pattern who exhibited rapidly increased tumor volume within two weeks after undergoing a third trans-arterial chemoembolization (TACE). Although the Barcelona Clinic Liver Cancer staging system classifies multinodular HCC without portal invasion or extrahepatic spread in stage B, it appears that TACE is not suitable for those with a large tumor burden or infiltrative tumor pattern. In addition, hypoxia is an important factor for tumor development, metastasis, and drug resistance. Our case suggests that intense hypoxia induced by TACE may lead to the rapid progression of HCC. |
| Publish Date |
2023-06-30 12:54 |
| Citation |
Yeo KF, Ker A, Kao PE, Wang CC. Hypothetical hypoxia-driven rapid disease progression in hepatocellular carcinoma post transarterial chemoembolization: A case report. World J Clin Cases 2023; 11(19): 4664-4669 |
| URL |
https://www.wjgnet.com/2307-8960/full/v11/i19/4664.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v11.i19.4664 |
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