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Articles Published Processes
5/24/2023 9:31:05 AM | Browse: 242 | Download: 671
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Received |
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2023-01-29 00:29 |
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Peer-Review Started |
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2023-01-29 00:33 |
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To Make the First Decision |
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Return for Revision |
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2023-02-23 05:20 |
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Revised |
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2023-03-14 01:09 |
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Second Decision |
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2023-04-10 03:09 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-04-10 08:08 |
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Articles in Press |
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2023-04-10 08:08 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-05-17 07:46 |
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Publish the Manuscript Online |
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2023-05-24 09:31 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Noninvasive biomarkers in pediatric nonalcoholic fatty liver disease
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Dulshan Jayasekera and Phillipp Hartmann |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| University of California San Diego Altman Clinical and Translational Research Institute (ACTRI)/NIH grant |
KL2TR001444 |
| Pinnacle Research Award in Liver Diseases from the American Association for the Study of Liver Diseases Foundation |
PNC22-159963 |
| National Institutes of Health (NIH) |
K12 HD85036 |
| the Pilot/Feasibility Grant of the San Diego Digestive Diseases Research Center (SDDRC) |
P30 DK120515 (to P.H.) |
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| Corresponding Author |
Phillipp Hartmann, MD, Assistant Professor, Department of Pediatrics, Division of Pediatric Gastroenterology, Hepatology, and Nutrition, University of California San Diego, 9500 Gilman Dr, La Jolla, CA 92093, United States. phhartmann@health.ucsd.edu |
| Key Words |
Nonalcoholic fatty liver disease; Nonalcoholic steatohepatitis; Steatosis; Fibrosis; Serological; Imaging |
| Core Tip |
Nonalcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease in children and adolescents worldwide. Early diagnosis is essential and currently, liver biopsy is the gold standard for diagnosis and staging. However, noninvasive serological biomarkers, composite scores, and imaging biomarkers are being extensively studied for the diagnosis of NAFLD, nonalcoholic steatohepatitis (NASH), and liver fibrosis in children. This work reviews recent research on noninvasive biomarkers in pediatric NAFLD, identifies circulating biomarkers and imaging techniques that show the most promise, and suggests topics for future research. |
| Publish Date |
2023-05-24 09:31 |
| Citation |
Jayasekera D, Hartmann P. Noninvasive biomarkers in pediatric nonalcoholic fatty liver disease. World J Hepatol 2023; 15(5): 609-640 |
| URL |
https://www.wjgnet.com/1948-5182/full/v15/i5/609.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v15.i5.609 |
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