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Articles Published Processes
6/1/2023 1:04:32 PM | Browse: 220 | Download: 658
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Received |
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2023-02-02 07:06 |
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Peer-Review Started |
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2023-02-02 07:09 |
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To Make the First Decision |
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Return for Revision |
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2023-03-08 02:47 |
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Revised |
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2023-03-13 06:10 |
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Second Decision |
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2023-05-05 03:09 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-05-06 01:25 |
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Articles in Press |
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2023-05-06 01:25 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-05-26 08:48 |
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Publish the Manuscript Online |
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2023-06-01 13:04 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Effects of ethanol and sex on propionate metabolism evaluated via a faster 13C-propionate breath test in rats
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yosuke Sasaki, Naoyuki Kawagoe, Tsunehiko Imai and Yoshihisa Urita |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the Japan Society for the Promotion of Science KAKENHI Grant |
JP21K18089 |
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| Corresponding Author |
Yosuke Sasaki, MD, PhD, Assistant Professor, Lecturer, Department of General Medicine and Emergency Care, Toho University School of Medicine, 6-11-1 Omori-Nishi, Ota-Ku, Tokyo 143-8541, Japan. yousuke.sasaki@med.toho-u.ac.jp |
| Key Words |
Alcoholism; Breath test; Carbon isotope; Gut flora; Propionate; Vitamin B12 |
| Core Tip |
Alcoholism is a risk factor for vitamin B12 (VB12) deficiency. The 13C-propionate breath test (PBT) is a diagnostic modality for VB12 deficiency, but requires 2 h for completion. We applied a faster PBT to evaluate propionate metabolism using an ethanol-fed rat model. After 13C-propionate administration, the 13CO2/12CO2 isotope ratio of gas collected every 5 min for 60 min was measured using infrared isotope spectrometry. The Δ13CO2 peak occurred within 30 min. Ethanol-fed males showed marked propionate metabolism without associated liver injury. This study demonstrates the potential of the faster PBT to evaluate propionate metabolism under various clinical conditions. |
| Publish Date |
2023-06-01 13:04 |
| Citation |
Sasaki Y, Kawagoe N, Imai T, Urita Y. Effects of ethanol and sex on propionate metabolism evaluated via a faster 13C-propionate breath test in rats. World J Gastroenterol 2023; 29(21): 3269-3279 |
| URL |
https://www.wjgnet.com/1007-9327/full/v29/i21/3269.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v29.i21.3269 |
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