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5/11/2023 8:05:04 AM | Browse: 229 | Download: 752
Publication Name World Journal of Gastroenterology
Manuscript ID 83762
Country China
Received
2023-03-02 00:26
Peer-Review Started
2023-02-28 07:22
To Make the First Decision
Return for Revision
2023-03-14 07:14
Revised
2023-03-16 13:10
Second Decision
2023-04-13 03:05
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2023-04-13 08:34
Articles in Press
2023-04-13 08:34
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2023-05-04 08:28
Publish the Manuscript Online
2023-05-11 08:05
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Biochemistry & Molecular Biology
Manuscript Type Basic Study
Article Title BanXiaXieXin decoction treating gastritis mice with drug-resistant Helicobacter pylori and its mechanism
Manuscript Source Unsolicited Manuscript
All Author List Xiao-Hua Li, Jia-Yin Xu, Xue Wang, Li-Juan Liao, Liang Huang, Yan-Qiang Huang and Zeng-Feng Zhang
ORCID
Author(s) ORCID Number
Xiao-Hua Li http://orcid.org/0000-0002-8576-3044
Jia-Yin Xu http://orcid.org/0000-0003-0423-5846
Xue Wang http://orcid.org/0000-0003-3931-8107
Li-Juan Liao http://orcid.org/0000-0003-0547-2026
Liang Huang http://orcid.org/0000-0001-7937-8150
Yan-Qiang Huang http://orcid.org/0000-0002-0867-0178
Zeng-Feng Zhang http://orcid.org/0000-0003-2850-1889
Funding Agency and Grant Number
Funding Agency Grant Number
China National Natural Science Foundation 81760739
Special Fund Projects for Guide Local Science and Technology Development by the China government GUIKEZY20198004
2022 Guangxi Graduate Education Innovation Plan project YCBZ2022071
Corresponding Author Liang Huang, MD, Doctor, Doctor, Key Laboratory of the Prevention and Treatment of Drug Resistant Microbial Infecting, Youjiang Medical University for Nationalities, No. 98 Chengcheng Road, Youjiang District, Baise 533000, Guangxi Zhuang Autonomous Region, China. youyihuangl@163.com
Key Words Banxia Xiexin decoction; Helicobacter pylori; Drug resistance; Therapeutic effects; Mechanism
Core Tip The failure rate of treating Helicobacter pylori (Hp) infectious diseases is increasing, leading to an urgent need to study and develop anti-Hp drugs. Banxia Xiexin decoction (BXXX) has a good effect on Hp infection and Hp-infection-related diseases. However, its pharmacological mechanism remains unclear, and whether it has an effect on drug-resistant Hp infection has not been confirmed by animal experiments. Our study confirms that BXXX decoction (BXXXT) has good therapeutic effects on drug-resistant Hp infection through in vivo and in vitro experiments in mice, then the composition of BXXXT and effective components, the immunomodulatory effect, the main target were verified. We preliminarily explain why BXXXT has a good effects.
Publish Date 2023-05-11 08:05
Citation Li XH, Xu JY, Wang X, Liao LJ, Huang L, Huang YQ, Zhang ZF. BanXiaXieXin decoction treating gastritis mice with drug-resistant Helicobacter pylori and its mechanism. World J Gastroenterol 2023; 29(18): 2818-2835
URL https://www.wjgnet.com/1007-9327/full/v29/i18/2818.htm
DOI https://dx.doi.org/10.3748/wjg.v29.i18.2818
Full Article (PDF) WJG-29-2818.pdf
Full Article (Word) WJG-29-2818.docx
The ARRIVE Guidelines 83762-The-ARRIVE-Guidelines-revision.pdf
Manuscript File 83762_Auto_Edited-JLW.docx
Answering Reviewers 83762-Answering reviewers.pdf
Audio Core Tip 83762-Audio core tip.mp3
Biostatistics Review Certificate 83762-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 83762-Conflict-of-interest statement.pdf
Copyright License Agreement 83762-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 83762-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 83762-Institutional animal care and use committee statement.pdf
Non-Native Speakers of English Editing Certificate 83762-Language certificate.pdf
Peer-review Report 83762-Peer-review(s).pdf
Scientific Misconduct Check 83762-Bing-Chen YL-2.png
Scientific Editor Work List 83762-Scientific editor work list.pdf
CrossCheck Report 83762-CrossCheck report.pdf