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Articles Published Processes
5/11/2023 8:05:04 AM | Browse: 229 | Download: 752
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Received |
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2023-03-02 00:26 |
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Peer-Review Started |
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2023-02-28 07:22 |
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To Make the First Decision |
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Return for Revision |
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2023-03-14 07:14 |
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Revised |
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2023-03-16 13:10 |
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Second Decision |
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2023-04-13 03:05 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-04-13 08:34 |
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Articles in Press |
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2023-04-13 08:34 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-05-04 08:28 |
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Publish the Manuscript Online |
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2023-05-11 08:05 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Biochemistry & Molecular Biology |
Manuscript Type |
Basic Study |
Article Title |
BanXiaXieXin decoction treating gastritis mice with drug-resistant Helicobacter pylori and its mechanism
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Xiao-Hua Li, Jia-Yin Xu, Xue Wang, Li-Juan Liao, Liang Huang, Yan-Qiang Huang and Zeng-Feng Zhang |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
China National Natural Science Foundation |
81760739 |
Special Fund Projects for Guide Local Science and Technology Development by the China government |
GUIKEZY20198004 |
2022 Guangxi Graduate Education Innovation Plan project |
YCBZ2022071 |
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Corresponding Author |
Liang Huang, MD, Doctor, Doctor, Key Laboratory of the Prevention and Treatment of Drug Resistant Microbial Infecting, Youjiang Medical University for Nationalities, No. 98 Chengcheng Road, Youjiang District, Baise 533000, Guangxi Zhuang Autonomous Region, China. youyihuangl@163.com |
Key Words |
Banxia Xiexin decoction; Helicobacter pylori; Drug resistance; Therapeutic effects; Mechanism |
Core Tip |
The failure rate of treating Helicobacter pylori (Hp) infectious diseases is increasing, leading to an urgent need to study and develop anti-Hp drugs. Banxia Xiexin decoction (BXXX) has a good effect on Hp infection and Hp-infection-related diseases. However, its pharmacological mechanism remains unclear, and whether it has an effect on drug-resistant Hp infection has not been confirmed by animal experiments. Our study confirms that BXXX decoction (BXXXT) has good therapeutic effects on drug-resistant Hp infection through in vivo and in vitro experiments in mice, then the composition of BXXXT and effective components, the immunomodulatory effect, the main target were verified. We preliminarily explain why BXXXT has a good effects. |
Publish Date |
2023-05-11 08:05 |
Citation |
Li XH, Xu JY, Wang X, Liao LJ, Huang L, Huang YQ, Zhang ZF. BanXiaXieXin decoction treating gastritis mice with drug-resistant Helicobacter pylori and its mechanism. World J Gastroenterol 2023; 29(18): 2818-2835 |
URL |
https://www.wjgnet.com/1007-9327/full/v29/i18/2818.htm |
DOI |
https://dx.doi.org/10.3748/wjg.v29.i18.2818 |
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