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Articles Published Processes
6/25/2023 2:17:08 PM | Browse: 167 | Download: 540
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Received |
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2023-02-27 05:28 |
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Peer-Review Started |
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2023-02-27 05:31 |
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To Make the First Decision |
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Return for Revision |
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2023-03-29 01:13 |
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Revised |
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2023-04-03 06:34 |
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Second Decision |
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2023-04-24 02:53 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-04-24 08:56 |
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Articles in Press |
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2023-04-24 08:56 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2023-04-20 21:35 |
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Typeset the Manuscript |
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2023-06-14 00:50 |
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Publish the Manuscript Online |
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2023-06-25 14:17 |
ISSN |
1948-5182 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Review |
Article Title |
Ductular reaction in non-alcoholic fatty liver disease: When Macbeth is perverted
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Manuscript Source |
Invited Manuscript |
All Author List |
Yang-Huan He, Jia-Xing Pan, Lei-Ming Xu, Ting Gu and Yuan-Wen Chen |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Natural Science Foundation of China (General Program) |
81970511 |
National Natural Science Foundation of China (General Program) |
82270620 |
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Corresponding Author |
Yuan-Wen Chen, MD, PhD, Chief Physician, Director, Director, Doctor, Doctor, Department of Gastroenterology & Department of Geriatrics, Huadong Hospital Affiliated to Fudan University, No. 221 West Yan 'an Road, Shanghai 200040, China. chenywhdgi@fudan.edu.cn |
Key Words |
Ductular reaction; Non-alcoholic steatohepatitis; Hepatic progenitor cells; Cell differentiation; Inflammatory cells; Liver fibrosis |
Core Tip |
This is the first review focusing on recent advances in the relationship of hepatic cells with ductular reaction (DR), in fatty liver-related steatohepatitis and fibrosis. Recent advances in DR, a common compensatory reaction in liver injury, shed light on the effects of hepatic progenitor cells, hepatic stellate cells, myofibroblasts, inflammatory cells, and their secreted substance. In particular, hepatic progenitor cell differentiation was thoroughly discussed in developing steatohepatitis and fibrosis. This review summarizes the correlation between DR and steatohepatitis and fibrosis, the advanced stages of non-alcoholic fatty liver disease, or metabolic (dysfunction) related fatty liver disease. |
Publish Date |
2023-06-25 14:17 |
Citation |
He Y, Pan J, Xu L, Gu T, Chen Y. Ductular reaction in non-alcoholic fatty liver disease: When Macbeth is perverted. World J Hepatol 2023; 15(6): 725-740 |
URL |
https://www.wjgnet.com/1948-5182/full/v15/i6/725.htm |
DOI |
https://dx.doi.org/10.4254/wjh.v15.i6.725 |
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