Publication Name	World Journal of Cardiology
Manuscript ID	8395
Country	Japan

Received	2014-01-08 17:49
Peer-Review Started	2014-01-13 09:45
To Make the First Decision	2014-02-13 16:23
Return for Revision	2014-02-19 10:59
Revised	2014-03-21 09:32
Second Decision	2014-06-27 17:45
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-06-27 18:03
Articles in Press	2014-06-27 18:03
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-08-28 13:59
Publish the Manuscript Online	2014-09-17 14:32

ISSN	1949-8462 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Cardiac & Cardiovascular Systems
Manuscript Type	Topic Highlights
Article Title	Peroxisome proliferator-activated receptors for hypertension
Manuscript Source	Invited Manuscript
All Author List	Daisuke Usuda and Tsugiyasu Kanda
Funding Agency and Grant Number
Corresponding Author	Daisuke Usuda, MD, MTM, Department of Community Medicine, Kanazawa Medical University Himi Municipal Hospital, 1130 Kurakawa, Himi-shi 935-8531, Toyama-ken, Japan. united19771108@yahoo.co.jp
Key Words	Peroxisome proliferator-activated receptors; Nuclear receptor; Isoform; mRNA; Blood pressure; Hypertension; Obesity; Angiotensin Ⅱ receptor blocker; Diabetes mellitus
Core Tip	Lifestyle-related diseases are major public health problem worldwide, and the prevalence of these diseases and subsequent complications has increased rapidly over the past 20 years. It has been a decade or more since the first report of the pleiotropic effects of peroxisome proliferator-activated receptors (PPARs), and numerous studies on their novel effects continue to appear every month. In addition to their effects on blood pressure, atherosclerosis, and kidney dysfunction, anti-cancer effects of PPARγ ligands have been reported recently. The effectiveness of PPAR agonists in the treatment of lifestyle-related diseases will be increasingly appreciated. This review summarizes the current literature on PPARs.
Publish Date	2014-09-17 14:32
Citation	Usuda D, Kanda T. Peroxisome proliferator-activated receptors for hypertension. World J Cardiol 2014; 6(8): 744-754
URL	http://www.wjgnet.com/1949-8462/full/v6/i8/744.htm
DOI	http://dx.doi.org/10.4330/wjc.v6.i8.744

Full Article (PDF)	WJC-6-744.pdf
Full Article (Word)	WJC-6-744.doc
Manuscript File	8395-Review.docx
Answering Reviewers	8395-Answering reviewers.pdf
Copyright License Agreement	8395-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	8395-Language certificate.pdf
Peer-review Report	8395-Peer review(s).pdf
Scientific Misconduct Check	8395-CrossCheck.jpg
Scientific Editor Work List	8395-Scientific editor work list.pdf