Publication Name	World Journal of Orthopedics
Manuscript ID	8396
Country	Japan

Received	2013-12-28 11:36
Peer-Review Started	2013-12-28 15:12
First Decision by Editorial Office Director
Return for Revision	2014-03-28 14:42
Revised	2014-04-14 14:53
Publication Fee Transferred
Second Decision by Editor	2014-07-17 14:19
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2014-07-17 14:37
Articles in Press	2014-07-17 14:53
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-08-11 08:36
Publish the Manuscript Online	2014-08-20 20:55

ISSN	2218-5836 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Rheumatology
Manuscript Type	Topic Highlights
Article Title	Inhibition of rheumatoid arthritis by blocking connective tissue growth factor
Manuscript Source	Invited Manuscript
All Author List	Kazuhisa Nozawa, Maki Fujishiro, Yoshinari Takasaki and Iwao Sekigawa
Funding Agency and Grant Number	Funding Agency Grant Number Scientific Research (C), The Ministry of Education, Culuture, Sports, Science and Technology Institute for Environment and Gender-specific Medicine, Juntendo University Graduate School of Medicine
Corresponding Author	Kazuhisa Nozawa, MD, PhD, Department of Rheumatology, School of Medicine, Juntendo University 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan. k-nozawa@juntendo.ac.jp
Key Words	Connective tissue growth facto; Rheumatoid arthritis; Osteoclasts; Condrocytes; Tumor necrosis factor-α
Core Tip	Connective tissue growth factor (CTGF) plays an important role in the pathogenesis of rheumatoid arthritis (RA). We propose that CTGF is a potentially novel effector molecule in the pathogenesis of RA. Blocking the CTGF pathways by biological agents may have great beneficial effect in patients with RA.
Publish Date	2014-08-20 20:55
Citation	Nozawa K, Fujishiro M, Takasaki Y, Sekigawa I. Inhibition of rheumatoid arthritis by blocking connective tissue growth factor.
URL	http://www.wjgnet.com/2218-5836/full/v5/i5/653.htm
DOI	http://dx.doi.org/10.5312/wjo.v5.i5.653

Full Article (PDF)	WJO-5-653.pdf
Full Article (Word)	WJO-5-653.doc
Manuscript File	8396-Review.docx
Answering Reviewers	8396-Answering reviewers.pdf
Copyright License Agreement	8396-Copyright assignment.pdf
Peer-review Report	8396-Peer review(s).pdf
Scientific Misconduct Check	8396-CrossCheck.jpg
Scientific Editor Work List	8396-Scientific editor work list.pdf