Publication Name	World Journal of Medical Genetics
Manuscript ID	8401
Country	Japan

Received	2013-12-28 11:49
Peer-Review Started	2013-12-28 15:32
To Make the First Decision	2014-02-13 16:23
Return for Revision	2014-02-20 23:54
Revised	2014-02-25 19:30
Second Decision	2014-03-17 14:37
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-03-17 14:48
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-03-23 01:00
Typeset the Manuscript	2014-05-27 18:58
Publish the Manuscript Online	2014-05-28 15:12

ISSN	2220-3184 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Virology
Manuscript Type	Review
Article Title	Molecular epidemiology of hepatitis B virus in Asia
Manuscript Source	Invited Manuscript
All Author List	Takako Utsumi, Yoshihiko Yano and Hak Hotta
Funding Agency and Grant Number	Funding Agency Grant Number Japan Initiative for Global Research Network on Infectious Diseases (J-GRID) Program from the Ministry of Education, Culture, Sports, Science and Technology, Japan Ministry of Health, Labour and Welfare, Japan SATREPS Grant from Japan Science and Technology Agency and Japan International Cooperation Agency
Corresponding Author	Hak Hotta, MD, PhD, Center for Infectious Diseases, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan. hotta@kobe-u.ac.jp
Key Words	Hepatitis B virus; Genotype; Subgenotype; Molecular epidemiology; Asia; Pathogenicity; Drug resistance
Core Tip	Chronic hepatitis B virus (HBV) infection usually progresses to liver cirrhosis and hepatocellular carcinoma. The variation of the HBV genotype is related to the geographical distribution. Also, the clinical characteristics and therapeutic effectiveness of interferon and nucleos(t)ide analogue vary among different HBV genotypes. A large number of epidemiological and clinical studies have been reported from Asian countries. However, most of the studies were conducted in developed countries such as Taiwan, China, South Korea and Japan. In this review, epidemiologically and clinically important aspects of HBV genotypes/subgenotypes found in East and Southeast Asian countries are updated and summarized.
Publish Date	2014-05-28 15:12
Citation	Utsumi T, Yano Y, Hotta H. Molecular epidemiology of hepatitis B virus in Asia. World J Med Genet 2014; 4(2): 19-26
URL	http://www.wjgnet.com/2220-3184/full/v4/i2/19.htm
DOI	http://dx.doi.org/10.5496/wjmg.v4.i2.19

Full Article (PDF)	WJMG-4-19.pdf
Full Article (Word)	WJMG-4-19.doc
Manuscript File	8401-Review.docx
Answering Reviewers	8401-Answering reviewers.pdf
Copyright License Agreement	8401-Copyright assignment.pdf
Peer-review Report	8401-Peer reviewer(s).pdf
Scientific Editor Work List	8401-Scientific editor work list.doc