Publication Name	World Journal of Gastroenterology
Manuscript ID	8403
Country	China

Received	2013-12-28 11:53
Peer-Review Started	2013-12-28 15:40
To Make the First Decision	2014-01-09 14:42
Return for Revision	2014-01-17 14:54
Revised	2014-01-23 22:23
Second Decision	2014-03-06 17:54
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-03-06 18:08
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-03-13 00:15
Typeset the Manuscript	2014-03-13 19:34
Publish the Manuscript Online	2014-04-14 10:49

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Medicine, Research & Experimental
Manuscript Type	Evidence-Based Medicine
Article Title	Combined detection tumor markers for diagnosis and prognosis of gallbladder cancer
Manuscript Source	Unsolicited Manuscript
All Author List	Yun-Feng Wang, Fei-Ling Feng, Xu-Hong Zhao, Zhen-Xiong Ye, He-Ping Zeng, Zhen Li, Xiao-Qing Jiang and Zhi-Hai Peng
Funding Agency and Grant Number
Corresponding Author	Yun-Feng Wang, PhD, Department of General Surgery, Yangpu Hospital, Tongji University School of Medicine, No. 450, Teng Yue Road, Shanghai 200090, China. wangyunfeng197911@163.com
Key Words	Gallbladder cancer; Tumor marker; Combined detection; Diagnosis; Prognosis
Core Tip	Detection of serum tumor markers is simple, and has become a common clinical method for tumor screening. However, when these markers are used individually for the diagnosis of gallbladder cancer, inconsistent results have been obtained. The results of the present study suggest that combined detection of serum cancer antigens cancer antigens (CA)125, CA199, and CA242 can increase the specificity of gallbladder cancer (GBC) diagnosis. CA242 could be regarded as a tumor marker of GBC infiltration in the early stage. Multivariate survival analysis showed that cancer of the gallbladder neck and CA199 expression levels were independent prognostic factors.
Publish Date	2014-04-14 10:49
Citation	Wang YF, Feng FL, Zhao XH, Ye ZX, Zeng HP, Li Z, Jiang XQ, Peng ZH. Combined detection tumor markers for diagnosis and prognosis of gallbladder cancer. World J Gastroenterol 2014; 20(14): 4085-4092
URL	http://www.wjgnet.com/1007-9327/full/v20/i14/4085.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i14.4085

Full Article (PDF)	WJG-20-4085.pdf
Full Article (Word)	WJG-20-4085.doc
Manuscript File	8403-Review.doc
Answering Reviewers	8403-Answering reviewers.pdf
Copyright License Agreement	8403-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	8403-Language certificate.PDF
Peer-review Report	8403-Peer reviews.pdf
Scientific Editor Work List	8403-Scientific editor work list.doc