ISSN |
2307-8960 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Review |
Article Title |
Liver replacement therapy with extracorporeal blood purification techniques current knowledge and future directions
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Manuscript Source |
Invited Manuscript |
All Author List |
Panagiotis Papamichalis, Katerina G Oikonomou, Asimina Valsamaki, Maria Xanthoudaki, Periklis Katsiafylloudis, Evangelia Papapostolou, Apostolia-Lemonia Skoura, Michail Papamichalis, Marios Karvouniaris, Antonios Koutras, Eleni Vaitsi, Smaragdi Sarchosi, Antonios Papadogoulas and Dimitrios Papadopoulos |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Panagiotis Papamichalis, MD, PhD, Consultant Physician-Scientist, Doctor, Doctor, Intensive Care Unit, General Hospital of Larissa, 1 Tsakalof, Larissa 41221, Thessaly, Greece. ppapamih@med.uth.gr |
Key Words |
Liver failure; Transplantation; Blood purification; Liver replacement therapy; Artificial extracorporeal systems; Transplant-free survival |
Core Tip |
Elimination of liver toxins during liver failure is a highly difficult and complex process and demands a combination of multiple methods. Although the evolution of artificial extracorporeal systems is remarkable, it is still insufficient to meet the current therapeutic demands. Several methods and circuits are available, each one with different features, advantages, and disadvantages. There is an urgent need for more research, randomized controlled trials, and evidence. Implementation of protocols combining the available techniques in response to each patient’s special needs is probably the key to personalized treatment, as bridging therapy either to recovery or to liver transplantation. |
Publish Date |
2023-06-12 08:16 |
Citation |
Papamichalis P, Oikonomou KG, Valsamaki A, Xanthoudaki M, Katsiafylloudis P, Papapostolou E, Skoura AL, Papamichalis M, Karvouniaris M, Koutras A, Vaitsi E, Sarchosi S, Papadogoulas A, Papadopoulos D. Liver replacement therapy with extracorporeal blood purification techniques current knowledge and future directions. World J Clin Cases 2023; 11(17): 3932-3948 |
URL |
https://www.wjgnet.com/2307-8960/full/v11/i17/3932.htm |
DOI |
https://dx.doi.org/10.12998/wjcc.v11.i17.3932 |