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Articles Published Processes
7/12/2023 7:57:45 AM | Browse: 180 | Download: 583
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Received |
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2023-02-28 14:29 |
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Peer-Review Started |
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2023-02-28 14:32 |
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To Make the First Decision |
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Return for Revision |
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2023-04-10 07:23 |
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Revised |
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2023-04-22 13:52 |
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Second Decision |
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2023-06-13 02:58 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-06-13 08:31 |
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Articles in Press |
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2023-06-13 08:31 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2023-06-11 18:55 |
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Typeset the Manuscript |
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2023-07-05 04:32 |
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Publish the Manuscript Online |
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2023-07-12 07:57 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Infectious Diseases |
| Manuscript Type |
Case Report |
| Article Title |
ABCB4 gene mutation-associated cirrhosis with systemic amyloidosis: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Na Cheng, Yu-Jie Qin, Quan Zhang and Hong Li |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| The Department of Science and Technology of Guizhou Province |
[2020]1Y299 |
| National Natural Science Foundation of China |
82060123 |
| National Health Commission of Guizhou Province |
gzwjk2019-1-082 |
| Doctor Start Fund of Affiliated Hospital of Guizhou Medical University |
gyfybsky-2021-28 |
| National Natural Cultivation Fund of Affiliated Hospital of Guizhou Medical University |
I-2020-12 |
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| Corresponding Author |
Hong Li, MD, PhD, Doctor, Doctor, Department of Infectious Diseases, Guizhou Provincial People's Hospital, P.O. Box No. 83 Zhongshan East Road, Nanming District, Guiyang 550025, Guizhou Province, China. 625062102@qq.com |
| Key Words |
ABCB4 gene; Progressive familial intrahepatic cholestasis 3; Cirrhosis; Systemic amyloidosis; Case report |
| Core Tip |
We report a unique case of liver cirrhosis resulting from a mutation in the ATP-binding cassette, subfamily B (ABCB4) gene in conjunction with primary light chain amyloidosis. This disease exhibits clinical manifestations such as portal hypertension, recurrent ascites, and jaundice. Intractable proteinuria, peripheral neuropathy, and gradual cardiac function damage may also appear during disease progression. Congo red staining of the liver, spleen, bone marrow, and kidney, as well as kidney immunohistochemistry and liver mass spectrometry allowed a final diagnosis to be made. The patient exhibited improvement after treatment with a combination of ursodeoxycholic acid and CD38 monoclonal antibody daratumumab. |
| Publish Date |
2023-07-12 07:57 |
| Citation |
Cheng N, Qin YJ, Zhang Q, Li H. ABCB4 gene mutation-associated cirrhosis with systemic amyloidosis: A case report. World J Clin Cases 2023; 11(20): 4903-4911 |
| URL |
https://www.wjgnet.com/2307-8960/full/v11/i20/4903.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v11.i20.4903 |
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