Publication Name	World Journal of Gastroenterology
Manuscript ID	8423
Country	Italy

Received	2013-12-28 13:13
Peer-Review Started	2013-12-28 17:38
First Decision by Editorial Office Director
Return for Revision	2014-01-17 14:43
Revised	2014-02-15 04:13
Publication Fee Transferred
Second Decision by Editor	2014-05-29 19:34
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2014-05-29 19:51
Articles in Press	2014-05-29 20:07
Edit the Manuscript by Language Editor	2014-06-10 14:57
Typeset the Manuscript	2014-08-11 11:11
Publish the Manuscript Online	2014-08-29 11:57

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Post-liver transplant hepatitis C virus recurrence: An unresolved thorny problem
Manuscript Source	Invited Manuscript
All Author List	Alberto Grassi and Giorgio Ballardini
Funding Agency and Grant Number
Corresponding Author	Correspondence to: Alberto Grassi, MD, PhD, Internal Medicine and Hepatology Division, Department of Internal Medicine, “Infermi” Hospital, Viale Settembrini 2, 47923 Rimini, Italy. albgrassi@yahoo.com
Key Words	Hepatitis C virus; Liver transplantation; Hepatitis C antigens; Graft rejection; Immunosuppression
Core Tip	Hepatitis C virus (HCV) graft reinfection universally occurs post-liver transplantation and disease progression is accelerated. Differentiating recurrent hepatitis from rejection is essential in this setting; however, differentiation of the two pathological patterns remains difficult. The host immune response appears to be crucial both in the control of HCV infection and in the genesis of rejection: complete prevention of rejection and optimization of immunosuppression should represent the main goals. A proper graft allocation seems to be crucial to realize an ideal donor-to-recipient matching; however, many factors remain obscure.
Publish Date	2014-08-29 11:57
Citation	Grassi A, Ballardini G. Post-liver transplant hepatitis C virus recurrence: An unresolved thorny problem. World J Gastroenterol 2014; 20(32): 11095-11115
URL	http://www.wjgnet.com/1007-9327/full/v20/i32/11095.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i32.11095

Full Article (PDF)	WJG-20-11095.pdf
Full Article (Word)	WJG-20-11095.doc
Manuscript File	8423-Review.doc
Answering Reviewers	8423-Answering reviewers.pdf
Copyright License Agreement	8423-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	8423-Language certificate.pdf
Peer-review Report	8423-Peer reviews.pdf
Scientific Misconduct Check	8423-CrossCheck.jpg
Scientific Editor Work List	8423-Scientific editor work list.pdf