Publication Name	World Journal of Clinical Oncology
Manuscript ID	8433
Country	United States

Received	2013-12-28 14:01
Peer-Review Started	2013-12-28 18:14
To Make the First Decision	2014-02-13 16:22
Return for Revision	2014-04-18 08:44
Revised	2014-03-04 12:29
Second Decision	2014-04-19 14:25
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-04-19 14:35
Articles in Press	2014-05-23 09:11
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-05-08 19:13
Typeset the Manuscript	2014-07-18 10:11
Publish the Manuscript Online	2014-08-01 15:17

ISSN	2218-4333 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Topic Highlights
Article Title	Therapeutic options for HER-2 positive breast cancer: Perspectives and future directions
Manuscript Source	Invited Manuscript
All Author List	Gonzalo Recondo Jr, Enrique Dìaz Canton, Màximo de la Vega, Martin Greco, Gonzalo Recondo Sr and Matias E Valsecchi
Funding Agency and Grant Number
Corresponding Author	Matias E Valsecchi, MD, MS, Medical Oncology, HIMG, 5170 US Route 60 East, Huntington, WV 25705, United States. meval78@yahoo.com
Key Words	Breast cancer; Human epidermal growth factor receptor-2; Trastuzumab; Pertuzumab; Ado-trastuzumab; Lapatinib
Core Tip	This is a review manuscript with the most updated information regarding the state of the art management of human epidermal growth factor receptor-2 positive breast cancer. It summarizes the most relevant and updated information derived from more than 40 phase Ⅱ and Ⅲ clinical trials that constitute the theoretical framework to support our daily practice. It also highlights some key clinical concepts that should not be overlooked by critically appraising the current literature. Finally, it gives the reader with a compilation of potential new agents that are currently being tested and may soon become the next step in the battle against this disease.
Publish Date	2014-08-01 15:17
Citation	Recondo G Jr, Dìaz Canton E, de la Vega M, Greco M, Recondo G Sr, Valsecchi ME. Therapeutic options for HER-2 positive breast cancer: Perspectives and future directions. World J Clin Oncol 2014; 5(3): 440-454
URL	http://www.wjgnet.com/2218-4333/full/v5/i3/440.htm
DOI	http://dx.doi.org/10.5306/wjco.v5.i3.440

Full Article (PDF)	WJCO-5-440.pdf
Full Article (Word)	WJCO-5-440.doc
Manuscript File	8433-Review.doc
Answering Reviewers	8433-Answering reviewers.pdf
Copyright License Agreement	8433-Copyright assignment.pdf
Peer-review Report	8433-Peer review(s).pdf
Scientific Editor Work List	8433-Scientific editor work list.doc