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Articles Published Processes
7/21/2023 9:10:50 AM | Browse: 227 | Download: 588
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Received |
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2023-03-17 19:01 |
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Peer-Review Started |
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2023-03-17 19:04 |
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To Make the First Decision |
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Return for Revision |
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2023-05-30 19:51 |
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Revised |
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2023-06-07 02:52 |
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Second Decision |
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2023-06-13 02:58 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-06-13 08:59 |
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Articles in Press |
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2023-06-13 08:59 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-07-04 03:57 |
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Publish the Manuscript Online |
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2023-07-21 09:10 |
ISSN |
1948-5182 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Pathology |
Manuscript Type |
Minireviews |
Article Title |
Solid-Tubulocystic carcinoma: A new variant of intrahepatic cholangiocarcinoma
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Manuscript Source |
Invited Manuscript |
All Author List |
Iván A González, Wenyi Luo and Xuchen Zhang |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Xuchen Zhang, MD, PhD, Full Professor, Department of Pathology, Yale University School of Medicine, 300 Cedar Street, New Haven, CT 06511, United States. xuchen.zhang@yale.edu |
Key Words |
Cholangiocarcinoma; Intrahepatic; Solid-tubulocystic; Cholangioblastic; Inhibin |
Core Tip |
Solid-tubulocystic variant of intrahepatic cholangiocarcinoma (iCCA) is a recently recognized iCCA variant, which previously was termed as cholangioblastic iCCA. This new variant iCCA predominantly presents in young woman characterized by a heterogenous microscopic appearance with small to medium sized tumor cells with eosinophilic cytoplasm organized in solid, tubular, and cystic growth patterns. One of the defining features is the diffuse expression of inhibin. Recurrent NIPBL::NACC1 gene fusion has been identified in this iCCA variant. Compared to typical iCCAs, patients with this variant iCCA may have a better prognosis with 25% of the cases reported died of disease in 5 years. |
Publish Date |
2023-07-21 09:10 |
Citation |
González IA, Luo W, Zhang X. Solid-Tubulocystic carcinoma: A new variant of intrahepatic cholangiocarcinoma. World J Hepatol 2023; 15(7): 897-903 |
URL |
https://www.wjgnet.com/1948-5182/full/v15/i7/897.htm |
DOI |
https://dx.doi.org/10.4254/wjh.v15.i7.897 |
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