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6/28/2023 10:03:21 AM | Browse: 136 | Download: 323
Publication Name World Journal of Gastroenterology
Manuscript ID 84581
Country United Kingdom
Received
2023-03-20 13:55
Peer-Review Started
2023-03-20 13:58
To Make the First Decision
Return for Revision
2023-04-27 05:08
Revised
2023-05-05 21:38
Second Decision
2023-05-25 02:53
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2023-05-25 09:12
Articles in Press
2023-05-25 09:12
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2023-06-13 13:19
Publish the Manuscript Online
2023-06-28 10:03
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Retrospective Cohort Study
Article Title Regional variation in routes to diagnosis of cholangiocarcinoma in England from 2006 to 2017
Manuscript Source Unsolicited Manuscript
All Author List Amy Zalin-Miller, Sophie Jose, Craig Knott, Lizz Paley, Daniela Tataru, Helen Morement, Mireille B Toledano and Shahid A Khan
ORCID
Author(s) ORCID Number
Amy Zalin-Miller http://orcid.org/0000-0002-3123-3566
Sophie Jose http://orcid.org/0000-0002-3536-4344
Craig Knott http://orcid.org/0000-0002-8593-6216
Lizz Paley http://orcid.org/0000-0002-3879-5377
Daniela Tataru http://orcid.org/0009-0002-2655-4717
Helen Morement http://orcid.org/0000-0001-6141-2816
Mireille B Toledano http://orcid.org/0000-0001-5695-6210
Shahid A Khan http://orcid.org/0000-0003-2538-0911
Funding Agency and Grant Number
Funding Agency Grant Number
AMMF – The Cholangiocarcinoma Charity
Corresponding Author Amy Zalin-Miller, MSc, Senior Researcher, Department of Analytics, Health Data Insight CIC, Capital Park, Fulbourn, Cambridge CB21 5XE, United Kingdom. amy.zalin@nhs.net
Key Words Cholangiocarcinoma; Route to diagnosis; Two week wait; Emergency presentation; Regional variation
Core Tip We investigated changes to routes to diagnosis for cholangiocarcinoma patients across England’s 21 regional Cancer Alliances over a 12-year period, and factors associated with differences. We found almost half (49.6%) of 22632 patients in the study were diagnosed via Emergency Presentation, a route associated with late presentation, advanced disease and poorer outcomes. Those diagnosed by Two week wait referral through a primary care doctor, where earlier diagnoses are possible, increased from 9.8-19.8% from 2006-2017, still considered low. Significant regional variation was found, alongside the discovery that age, comorbidities and underlying liver disease had independent associations with their routes to diagnosis.
Publish Date 2023-06-28 10:03
Citation Zalin-Miller A, Jose S, Knott C, Paley L, Tataru D, Morement H, Toledano MB, Khan SA. Regional variation in routes to diagnosis of cholangiocarcinoma in England from 2006 to 2017. World J Gastroenterol 2023; 29(24): 3825-3842
URL https://www.wjgnet.com/1007-9327/full/v29/i24/3825.htm
DOI https://dx.doi.org/10.3748/wjg.v29.i24.3825
Full Article (PDF) WJG-29-3825-with-cover.pdf
Full Article (Word) WJG-29-3825.docx
STROBE Statement 84581-STROBE-Statement-revision.pdf
Manuscript File 84581_Auto_Edited-JLW.docx
Answering Reviewers 84581-Answering reviewers.pdf
Audio Core Tip 84581-Audio core tip.mp3
Biostatistics Review Certificate 84581-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 84581-Conflict-of-interest statement.pdf
Copyright License Agreement 84581-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 84581-Grant application form(s).pdf
Institutional Review Board Approval Form or Document 84581-Institutional review board statement.pdf
Supplementary Material 84581-Supplementary material.pdf
Peer-review Report 84581-Peer-review(s).pdf
Scientific Misconduct Check 84581-Bing-Li L-2.png
Scientific Editor Work List 84581-Scientific editor work list.pdf