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Articles Published Processes
9/8/2023 9:01:55 AM | Browse: 228 | Download: 596
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Received |
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2023-03-23 02:12 |
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Peer-Review Started |
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2023-03-23 02:14 |
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To Make the First Decision |
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Return for Revision |
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2023-06-17 11:52 |
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Revised |
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2023-07-15 10:01 |
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Second Decision |
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2023-08-14 02:57 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-08-15 09:11 |
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Articles in Press |
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2023-08-15 09:11 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2023-08-23 22:20 |
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Typeset the Manuscript |
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2023-09-05 08:35 |
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Publish the Manuscript Online |
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2023-09-08 09:01 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Suberoylanilide hydroxamic acid upregulates reticulophagy receptor expression and promotes cell death in hepatocellular carcinoma cells
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jia-Yao Li, Tian Tian, Bing Han, Ting Yang, Yi-Xin Guo, Jia-Yu Wu, Yu-Si Chen, Qin Yang and Ru-Jia Xie |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
82260127 |
| Guizhou Provincial Science and Technology Projects |
Qiankehe Jichu-ZK[2021]365 |
| Guizhou Provincial Science and Technology Projects |
Qiankehe Jichu-ZK[2021]364 |
| National Natural Science Foundation Cultivation Project of Guizhou Medical University |
20NSP016 |
| Guizhou Provincial Natural Science Foundation |
[2021]4029, [2022]4017 |
| Science and Technology Foundation of Guizhou Provincial Health Commission |
gzwjkj2019-1-102 |
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| Corresponding Author |
Ru-Jia Xie, MD, Academic Research, Department of Pathophysiology, College of Basic Medical Sciences, Guizhou Medical University, Dongqing Road, Guiyang 550025, Guizhou Province, China. 592153968@qq.com |
| Key Words |
Suberoylanilide hydroxamic acid; Histone H4 lysine-16; Reticulophagy; Apoptosis; Autophagic cell death; Hepatocellular carcinoma |
| Core Tip |
Family with sequence similarity 134 member B (FAM134B) is considered to be a tumor suppressor protein that can play a pivotal role in inhibiting hepatocellular carcinoma (HCC) cells. In addition, FAM134B acts as a putative reticulophagy receptor in the regulation of the reticulophagy process. Furthermore, suberoylanilide hydroxamic acid (SAHA) upregulates FAM134B expression in HCC cells and promotes apoptosis and autophagy-mediated cell death. Thus, FAM134B-mediated reticulophagy synergizes with SAHA to induce HCC cell death. Our findings offer novel insights into the mechanism underlying SAHA-induced HCC cell death. |
| Publish Date |
2023-09-08 09:01 |
| Citation |
Li JY, Tian T, Han B, Yang T, Guo YX, Wu JY, Chen YS, Yang Q, Xie RJ. Suberoylanilide hydroxamic acid upregulates reticulophagy receptor expression and promotes cell death in hepatocellular carcinoma cells. World J Gastroenterol 2023; 29(34): 5038-5053 |
| URL |
https://www.wjgnet.com/1007-9327/full/v29/i34/5038.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v29.i34.5038 |
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