Publication Name	World Journal of Clinical Oncology
Manuscript ID	8465
Country	Taiwan

Received	2013-12-28 15:49
Peer-Review Started	2013-12-28 20:25
To Make the First Decision	2014-01-15 16:33
Return for Revision	2014-01-20 17:42
Revised	2014-02-10 15:28
Second Decision	2014-04-16 17:16
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-04-16 17:27
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-11-14 10:31
Publish the Manuscript Online	2014-12-11 14:23

ISSN	2218-4333 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Topic Highlights
Article Title	Tumour suppressor HLJ1: A potential diagnostic, preventive and therapeutic target in non-small cell lung cancer
Manuscript Source	Invited Manuscript
All Author List	Meng-Feng Tsai, Chi-Chung Wang and Jeremy JW Chen
Funding Agency and Grant Number	Funding Agency Grant Number National Science Council, Taiwan, ROC Ministry of Education, Taiwan, ROC under the ATU plan(In part)
Corresponding Author	Jeremy JW Chen, PhD, Professor, Institute of Biomedical Sciences, National Chung-Hsing University, No. 250, Kuo-Kuang Road, Taichung 40227, Taiwan. jwchen@dragon.nchu.edu.tw Telephone: +886-4-22840896, ext.125 Fax: +886-4-22853469
Key Words	Non-small cell lung cancer; Metastasis; HLJ1; Anticancer; Biomarker
Core Tip	HLJ1, a member of the human heat shock proteins 40 family, has been characterised as a tumour suppressor. Research studies have reported that HLJ1 shows promising dual anticancer effects, inhibiting both tumour growth and metastasis in non-small cell lung cancer (NSCLC). The accumulated evidence suggests that HLJ1 is a potential biomarker and treatment target for NSCLC. We propose a hypothetical model for the roles of HLJ1 stimulator in suppressing lung cancer tumourigenesis. Investigating the integrated and coordinated molecular mechanisms of HLJ1 may shed new light on the treatment of lung cancer. The development of drug targeting HLJ1 may be an effective approach for lung cancer therapy.
Publish Date	2014-12-11 14:23
Citation	Tsai MF, Wang CC, Chen JJW. Tumour suppressor HLJ1: A potential diagnostic, preventive and therapeutic target in non-small cell lung cancer. World J Clin Oncol 2014; 5(5): 865-873
URL	http://www.wjgnet.com/2218-4333/full/v5/i5/865.htm
DOI	http://dx.doi.org/10.5306/wjco.v5.i5.865

Full Article (PDF)	WJCO-5-865.pdf
Full Article (Word)	WJCO-5-865.doc
Manuscript File	8465-Review.docx
Answering Reviewers	8465-Answering reviewers.pdf
Copyright License Agreement	8465-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	8465-Language certificate.pdf
Peer-review Report	8465-Peer reviews.pdf
Scientific Editor Work List	8465-Scientific editor work list.doc