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8/10/2023 2:08:32 PM | Browse: 87 | Download: 243
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 84686
Country China
Received
2023-03-24 09:05
Peer-Review Started
2023-03-24 09:09
To Make the First Decision
Return for Revision
2023-05-19 12:25
Revised
2023-05-20 14:32
Second Decision
2023-06-19 02:51
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2023-06-19 06:57
Articles in Press
2023-06-19 06:57
Publication Fee Transferred
Edit the Manuscript by Language Editor
2023-06-17 09:44
Typeset the Manuscript
2023-08-02 03:03
Publish the Manuscript Online
2023-08-10 14:08
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Case Control Study
Article Title Fecal microbial biomarkers combined with multi-target stool DNA test improve diagnostic accuracy for colorectal cancer
Manuscript Source Unsolicited Manuscript
All Author List Jin-Qing Fan, Wang-Fang Zhao, Qi-Wen Lu, Fu-Rong Zha, Le-Bin Lv, Guo-Liang Ye and Han-Lu Gao
ORCID
Author(s) ORCID Number
Jin-Qing Fan http://orcid.org/0000-0001-6985-3261
Guo-Liang Ye http://orcid.org/0000-0003-0600-9981
Han-Lu Gao http://orcid.org/0000-0002-1066-0155
Funding Agency and Grant Number
Funding Agency Grant Number
Medical and Health Research Project of Zhejiang Province 2021KY1048, 2022KY1142
Ningbo Health Young Technical Backbone Talents Training Program 2020SWSQNGG-02
Key Science and Technology Project of Ningbo City 2021Z133
Corresponding Author Han-Lu Gao, PhD, Doctor, Department of Preventive Medicine, The First Hospital of Ningbo University, No. 247 Renmin Road, Ningbo 315000, Zhejiang Province, China. 306646058@qq.com
Key Words Gut microbiome; Colorectal cancer; Diagnostic model; Multi-target stool DNA test; Tumor biomarker
Core Tip There is a positive correlation of multi-target stool DNA (MT-sDNA), carcinoembryonic antigen (CEA), and alpha-fetoprotein with intestinal microbiome. Eight biomarkers including six genera of gut microbiota, MT-sDNA, and CEA showed a prominent sensitivity (98.1%) and specificity (92.3%) for colorectal cancer prediction, which could be used as a non-invasive method for improving the diagnostic accuracy for this malignancy.
Publish Date 2023-08-10 14:08
Citation Fan JQ, Zhao WF, Lu QW, Zha FR, Lv LB, Ye GL, Gao HL. Fecal microbial biomarkers combined with multi-target stool DNA test improve diagnostic accuracy for colorectal cancer. World J Gastrointest Oncol 2023; 15(8): 1424-1435
URL https://www.wjgnet.com/1948-5204/full/v15/i8/1424.htm
DOI https://dx.doi.org/10.4251/wjgo.v15.i8.1424
Full Article (PDF) WJGO-15-1424-with-cover.pdf
Full Article (Word) WJGO-15-1424.docx
Manuscript File 84686_Auto_Edited-JJW-WangTQ-JLW.docx
Answering Reviewers 84686-Answering reviewers.pdf
Audio Core Tip 84686-Audio core tip.m4a
Biostatistics Review Certificate 84686-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 84686-Conflict-of-interest statement.pdf
Copyright License Agreement 84686-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 84686-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 84686-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 84686-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 84686-Language certificate.pdf
Supplementary Material 84686-Supplementary material.pdf
Peer-review Report 84686-Peer-review(s).pdf
Scientific Misconduct Check 84686-Bing-Wang JJ-2.png
Scientific Editor Work List 84686-Scientific editor work list.pdf