Publication Name	World Journal of Gastroenterology
Manuscript ID	8477
Country	Canada

Received	2013-12-28 16:27
Peer-Review Started	2013-12-28 21:34
To Make the First Decision	2014-01-14 17:47
Return for Revision	2014-01-20 10:00
Revised	2014-02-16 03:17
Second Decision	2014-04-03 10:19
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-04-03 12:37
Articles in Press	2014-05-23 10:28
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-09-30 16:39
Typeset the Manuscript	2014-10-24 20:28
Publish the Manuscript Online	2014-11-10 19:10

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Surgery
Manuscript Type	Case Control Study
Article Title	Resistin is not an appropriate biochemical marker to predict severity of acute pancreatitis: A case-controlled study
Manuscript Source	Invited Manuscript
All Author List	Hamdi Al-Maramhy, Abdelrahman I Abdelrahman and Samer Sawalhi
Funding Agency and Grant Number	Funding Agency Grant Number Research grant from scientific research deanship -Taibah University 433/780
Corresponding Author	Samer Sawalhi, Assistant Professor, Surgical Consultant, Department of Surgery, College of Medicine, Dalhousie University, Suite 7-012, Victoria Building, VG Site1276, South Park Street, Halifax, NS B3H 2Y9, Canada. skyscraper555@yahoo.com
Key Words	Acute pancreatitis; Resistin; Body mass index; Waist circumference
Core Tip	Several predictive inflammatory markers have been used to predict pancreatitis severity. Peri-pancreatic adipose tissue synthesizes and secretes adipose-specific proteins, termed adipocytokines. One of these proteins, resistin, has immunomodulatory and metabolic activity. This novel adipose-driven protein, produced by pancreatic islets, may represent a useful additional marker for predicting acute pancreatitis (AP) severity. We found that serum resistin levels were significantly higher in patients with acute biliary pancreatitis compared to control subjects; however, resistin failed to serve as a predictive marker of clinical severity. Our study did find, however, that obesity correlated with severity of acute biliary pancreatitis. Based on the increased levels in AP patients upon hospital admission, we suggest that resistin could be used as a new diagnostic marker.
Publish Date	2014-11-10 19:10
Citation	Al-Maramhy H, Abdelrahman AI, Sawalhi S. Resistin is not an appropriate biochemical marker to predict severity of acute pancreatitis: A case-controlled study. World J Gastroenterol 2014; 20(41): 15351-15357
URL	http://www.wjgnet.com/1007-9327/full/v20/i41/15351.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i41.15351

Full Article (PDF)	WJG-20-15351.pdf
Full Article (Word)	WJG-20-15351.doc
Manuscript File	8477-Review.doc
Answering Reviewers	8477-Answering reviewers.pdf
Copyright License Agreement	8477-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	8477-Language certificate.pdf
Peer-review Report	8477-Peer reviews.pdf
Scientific Editor Work List	8477-Scientific editor work list.doc