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Articles Published Processes
6/28/2023 7:41:03 AM | Browse: 235 | Download: 563
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Received |
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2023-03-27 22:31 |
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Peer-Review Started |
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2023-03-27 22:34 |
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To Make the First Decision |
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Return for Revision |
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2023-05-12 08:21 |
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Revised |
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2023-05-22 13:49 |
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Second Decision |
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2023-06-06 02:39 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-06-06 10:14 |
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Articles in Press |
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2023-06-06 10:14 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-06-25 03:19 |
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Publish the Manuscript Online |
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2023-06-28 07:41 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Past, present, and future of long-term treatment for hepatitis B virus
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Teresa Broquetas and José A Carrión |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
José A Carrión, Doctor, MD, PhD, Assistant Professor, Liver Section, Gastroenterology Department, Hospital del Mar, 25-29 Passeig Marítim, Barcelona 08003, Spain. jcarrion@psmar.cat |
| Key Words |
Hepatitis B; Therapy; Antigen; Functional cure; Antiviral agents; Drug development |
| Core Tip |
Treatment for chronic hepatitis B has been used for decades, showing a good safety profile and high virological and clinical efficacy, decreasing hepatocellular carcinoma, clinical decompensation, and mortality. However, the low probability of hepatitis B virus surface antigen seroclearance with therapy made necessary indefinite treatment in a majority of patients. With the new insights about the immune system role in hepatitis B virus infection and the knowledge of the viral cycle phases, there has been in recent years increased activity in new therapeutic approaches. This review focuses on the past, present, and future of chronic hepatitis B therapy. |
| Publish Date |
2023-06-28 07:41 |
| Citation |
Broquetas T, Carrión JA. Past, present, and future of long-term treatment for hepatitis B virus. World J Gastroenterol 2023; 29(25): 3964-3983 |
| URL |
https://www.wjgnet.com/1007-9327/full/v29/i25/3964.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v29.i25.3964 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
