Publication Name	World Journal of Clinical Oncology
Manuscript ID	8479
Country	United States

Received	2013-12-28 16:35
Peer-Review Started	2013-12-28 21:16
To Make the First Decision	2014-03-12 17:03
Return for Revision	2014-03-21 09:01
Revised	2014-03-28 02:56
Second Decision	2014-04-29 08:23
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-04-29 08:37
Articles in Press	2014-05-23 09:09
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-07-24 14:15
Publish the Manuscript Online	2014-08-01 16:16

ISSN	2218-4333 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Topic Highlights
Article Title	Proton beam therapy for locally advanced lung cancer: A review
Manuscript Source	Invited Manuscript
All Author List	Steven E Schild, William G Rule, Jonathan B Ashman, Sujay A Vora, Sameer Keole, Aman Anand, Wei Liu and Martin Bues
Funding Agency and Grant Number	Funding Agency Grant Number Mayo Clinic
Corresponding Author	Steven E Schild, MD, Professor, Chair, Department of Radiation Oncology, Mayo Clinic Arizona, 13400 E, Shea Blvd, Scottsdale, AZ 85259, United States. schild.steven@mayo.edu
Key Words	Protons; Proton beam therapy; Lung cancer; Photons; X-rays; 3-D radiotherapy; Intensity modulated photon radiotherapy; Intensity modulated radiotherapy; Intensity modulated proton therapy
Core Tip	This review was written for the non-radiation oncologist who wishes to understand the use of proton beam therapy (PBT) for locally advanced lung cancer. PBT can be used to create treatment plans delivering significantly lower doses of radiation to the adjacent organs at risk (lungs, heart, esophagus, and bone marrow) than photon (X-ray) radiotherapy (XRT). PBT combined with chemotherapy has resulted in relatively low toxicity and favorable survival. One randomized study is being performed and another is planned to clarify the differences in outcome for PBT compared to XRT. Newer forms of radiotherapy such as PBT should positively impact lung cancer patients.
Publish Date	2014-08-01 16:16
Citation	Schild SE, Rule WG, Ashman JB, Vora SA, Keole S, Anand A, Liu W, Bues M. Proton beam therapy for locally advanced lung cancer: A review. World J Clin Oncol 2014; 5(4): 568-575
URL	http://www.wjgnet.com/2218-4333/full/v5/i4/568.htm
DOI	http://dx.doi.org/10.5306/wjco.v5.i4.568

Full Article (PDF)	WJCO-5-568.pdf
Full Article (Word)	WJCO-5-568.doc
Manuscript File	8479-Review.doc
Answering Reviewers	8479-Answering reviewers.pdf
Copyright License Agreement	8479-Copyright assignment.pdf
Peer-review Report	8479-Peer review(s).pdf
Scientific Editor Work List	8479-Scientific editor work list.doc