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Articles Published Processes
8/2/2023 9:29:03 AM | Browse: 389 | Download: 1455
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Received |
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2023-04-05 11:39 |
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Peer-Review Started |
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2023-04-05 11:41 |
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First Decision by Editorial Office Director |
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2023-05-23 11:12 |
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Return for Revision |
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2023-05-23 11:12 |
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Revised |
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2023-06-11 10:57 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2023-07-04 02:49 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2023-07-05 02:52 |
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Articles in Press |
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2023-07-05 02:52 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-07-19 06:14 |
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Publish the Manuscript Online |
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2023-08-02 09:29 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Antagonizing adipose tissue-derived exosome miR-103-hepatocyte phosphatase and tensin homolog pathway alleviates autophagy in non-alcoholic steatohepatitis: A trans-cellular crosstalk
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Miao-Miao Lu, Yue Ren, Yu-Wei Zhou, Ling-Ling Xu, Meng-Meng Zhang, Lin-Ping Ding, Wei-Xin Cheng and Xi Jin |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Natural Science Foundation of Zhejiang Province |
LZ21H030002 |
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| Corresponding Author |
Xi Jin, MD, PhD, Doctor, Doctor, Department of Gastroenterology, The First Affiliated Hospital of Zhejiang University School of Medicine, No. 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. jxfl007@zju.edu.cn |
| Key Words |
Non-alcoholic steatohepatitis; Nonalcoholic fatty liver disease; Exosomes; Phosphatase and tensin homolog |
| Core Tip |
Our study confirms the important role of miR-103-phosphatase and tensin homolog-autophagy axis in the pathogenesis of non-alcoholic steatohepatitis (NASH). More importantly, the elevation of miR-103 in the liver of NASH mice is partly due to adipose tissue exosome secretion and integration, which also partially explains the mechanism of obesity leading to NASH. |
| Publish Date |
2023-08-02 09:29 |
| Citation |
Lu MM, Ren Y, Zhou YW, Xu LL, Zhang MM, Ding LP, Cheng WX, Jin X. Antagonizing adipose tissue-derived exosome miR-103-hepatocyte phosphatase and tensin homolog pathway alleviates autophagy in non-alcoholic steatohepatitis: A trans-cellular crosstalk. World J Gastroenterol 2023; 29(29): 4528-4541 |
| URL |
https://www.wjgnet.com/1007-9327/full/v29/i29/4528.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v29.i29.4528 |
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