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8/25/2014 2:47:00 PM | Browse: 1114 | Download: 974
Publication Name World Journal of Gastroenterology
Manuscript ID 8501
Country China
Received
2013-12-29 15:26
Peer-Review Started
2013-12-29 20:25
To Make the First Decision
2014-01-09 14:29
Return for Revision
2014-01-17 13:05
Revised
2014-01-20 04:52
Second Decision
2014-03-06 17:55
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-03-06 18:08
Articles in Press
2014-05-23 11:16
Publication Fee Transferred
Edit the Manuscript by Language Editor
2014-03-17 17:16
Typeset the Manuscript
2014-06-26 10:27
Publish the Manuscript Online
2014-08-07 10:34
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Autobiography
Article Title RAD51 potentiates synergistic effects of chemotherapy with PCI-24781 and cis-diamminedichloroplatinum on gastric cancer
Manuscript Source Unsolicited Manuscript
All Author List Wei-Ling He, Yu-Huang Li, Wei-Jian Hou, Zun-Fu Ke, Xin-Lin Chen, Li-Ya Lu, Shi-Rong Cai, Wu Song, Chang-Hua Zhang and Yu-Long He
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 30973395
National Natural Science Foundation of China 81172337
National Natural Science Foundation of China 31271444
National Natural Science Foundation of China 81201726
Municipal Medicine Science and Technology Foundation of Guangzhou 201102A212012
Science and Technology Development Program of Guangdong 2012B031800115
Science Novel Program of Guangdong Education Department A2003165
Corresponding Author Yu-Long He, Professor, Department of Gastrointestinal and Pancreatic Surgery, The First Affiliated Hospital, Sun Yat-sen University, Binjiang Rd, Guangzhou 510080, Guangdong Province, China. hylsums@hotmail.com
Key Words Chemotherapy; Combination; Gastric cancer; Histone deacetylase inhibitor; Homologous recombination
Core Tip This is the first study to show that PCI-24781 synergizes with the chemotherapeutic effect of cis-diamminedichloroplatinum in gastric cancer in vivo and in vitro, and PCI-24781-induced RAD51 repression may be one of the mechanisms. PCI-24781 could be a potential drug and novel therapeutic strategy for the treatment of gastric cancer.
Publish Date 2014-08-07 10:34
Citation He WL, Li YH, Hou WJ, Ke ZF, Chen XL, Lu LY, Cai SR, Song W, Zhang CH, He YL. RAD51 potentiates synergistic effects of chemotherapy with PCI-24781 and cis-diamminedichloroplatinum on gastric cancer. World J Gastroenterol 2014; 20(29): 10094-10107
URL http://www.wjgnet.com/1007-9327/full/v20/i29/10094.htm
DOI http://dx.doi.org/10.3748/wjg.v20.i29.10094
Full Article (PDF) WJG-20-10094.pdf
Full Article (Word) WJG-20-10094.doc
Manuscript File 8501-Review.doc
Answering Reviewers 8501-Answering reviewers.pdf
Biostatistics Review Certificate Biostatistician_Review_Report_20131228092055.pdf
Copyright License Agreement 8501-Copyright assignment.pdf
Institutional Review Board Approval Form or Document Ethics_Committee_20131228092002.pdf
Non-Native Speakers of English Editing Certificate 8501-Language certificate.pdf
Peer-review Report 8501-Peer reviews.pdf
Scientific Editor Work List 8501-Scientific editor work list.doc