Publication Name	World Journal of Gastroenterology
Manuscript ID	8501
Country	China

Received	2013-12-29 15:26
Peer-Review Started	2013-12-29 20:25
First Decision by Editorial Office Director
Return for Revision	2014-01-17 13:05
Revised	2014-01-20 04:52
Publication Fee Transferred
Second Decision by Editor	2014-03-06 17:55
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2014-03-06 18:08
Articles in Press	2014-05-23 11:16
Edit the Manuscript by Language Editor	2014-03-17 17:16
Typeset the Manuscript	2014-06-26 10:27
Publish the Manuscript Online	2014-08-07 10:34

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Autobiography
Article Title	RAD51 potentiates synergistic effects of chemotherapy with PCI-24781 and cis-diamminedichloroplatinum on gastric cancer
Manuscript Source	Unsolicited Manuscript
All Author List	Wei-Ling He, Yu-Huang Li, Wei-Jian Hou, Zun-Fu Ke, Xin-Lin Chen, Li-Ya Lu, Shi-Rong Cai, Wu Song, Chang-Hua Zhang and Yu-Long He
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 30973395 National Natural Science Foundation of China 81172337 National Natural Science Foundation of China 31271444 National Natural Science Foundation of China 81201726 Municipal Medicine Science and Technology Foundation of Guangzhou 201102A212012 Science and Technology Development Program of Guangdong 2012B031800115 Science Novel Program of Guangdong Education Department A2003165
Corresponding Author	Yu-Long He, Professor, Department of Gastrointestinal and Pancreatic Surgery, The First Affiliated Hospital, Sun Yat-sen University, Binjiang Rd, Guangzhou 510080, Guangdong Province, China. hylsums@hotmail.com
Key Words	Chemotherapy; Combination; Gastric cancer; Histone deacetylase inhibitor; Homologous recombination
Core Tip	This is the first study to show that PCI-24781 synergizes with the chemotherapeutic effect of cis-diamminedichloroplatinum in gastric cancer in vivo and in vitro, and PCI-24781-induced RAD51 repression may be one of the mechanisms. PCI-24781 could be a potential drug and novel therapeutic strategy for the treatment of gastric cancer.
Publish Date	2014-08-07 10:34
Citation	He WL, Li YH, Hou WJ, Ke ZF, Chen XL, Lu LY, Cai SR, Song W, Zhang CH, He YL. RAD51 potentiates synergistic effects of chemotherapy with PCI-24781 and cis-diamminedichloroplatinum on gastric cancer. World J Gastroenterol 2014; 20(29): 10094-10107
URL	http://www.wjgnet.com/1007-9327/full/v20/i29/10094.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i29.10094

Full Article (PDF)	WJG-20-10094.pdf
Full Article (Word)	WJG-20-10094.doc
Manuscript File	8501-Review.doc
Answering Reviewers	8501-Answering reviewers.pdf
Biostatistics Review Certificate	Biostatistician_Review_Report_20131228092055.pdf
Copyright License Agreement	8501-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	Ethics_Committee_20131228092002.pdf
Non-Native Speakers of English Editing Certificate	8501-Language certificate.pdf
Peer-review Report	8501-Peer reviews.pdf
Scientific Editor Work List	8501-Scientific editor work list.doc