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Articles Published Processes
6/30/2023 12:54:07 PM | Browse: 303 | Download: 820
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Received |
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2023-04-10 13:42 |
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Peer-Review Started |
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2023-04-10 13:44 |
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To Make the First Decision |
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2023-05-12 01:23 |
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2023-05-22 04:44 |
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2023-05-31 03:10 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-05-31 07:52 |
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Articles in Press |
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2023-05-31 07:52 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-06-19 04:03 |
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Publish the Manuscript Online |
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2023-06-30 12:54 |
| Category |
Hematology |
| Manuscript Type |
Case Report |
| Article Title |
Tuberculosis-induced aplastic crisis and atypical lymphocyte expansion in advanced myelodysplastic syndrome: A case report and review of literature
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xiao-Yun Sun, Xiao-Dong Yang, Jia Xu, Nuan-Nuan Xiu, Bo Ju and Xi-Chen Zhao |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| The Specialized Scientific Research Fund Projects of The Medical Group of Qingdao University |
No: YLJT20201002 |
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| Corresponding Author |
Xi-Chen Zhao, MD, Chief Physician, Department of Hematology, The Central Hospital of Qingdao West Coast New Area, No 9, Huangpujiang Road, Qingdao 266555, Shandong Province, China. zhaoxichen2003@163.com |
| Key Words |
Case report; Myelodysplastic syndrome; Aplastc crisis; Atypical lymphocyte; Leukemic cell regression; CD56+ lymphocyte expansion; Disseminated tuberculosis |
| Core Tip |
In patients with myelodysplastic syndrome, bone marrow cellularity and myeloblasts usually increase with disease progression. An advanced myelodysplastic syndrome patient experienced an episode of aplastic crisis. During the aplastic crisis, leukemic cells regressed. The bone marrow was infiltrated with atypical lymphocytes that expressed high frequencies of cluster of differentiation (CD)3, CD5, CD8, CD16, CD56 and CD57. Antituberculosis treatment led to reversion of the aplastic crisis, disappearance of the atypical lymphocytes, increased marrow cellularity and 2 mo of hematological remission, suggesting that disseminated tuberculosis was responsible for the development of aplastic crisis, regression of leukemic cells and activation of CD56+ cells. |
| Publish Date |
2023-06-30 12:54 |
| Citation |
Sun XY, Yang XD, Xu J, Xiu NN, Ju B, Zhao XC. Tuberculosis-induced aplastic crisis and atypical lymphocyte expansion in advanced myelodysplastic syndrome: A case report and review of literature. World J Clin Cases 2023; 11(19): 4713-4722 |
| URL |
https://www.wjgnet.com/2307-8960/full/v11/i19/4713.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v11.i19.4713 |
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