Publication Name	World Journal of Gastrointestinal Endoscopy
Manuscript ID	85094
Country	Portugal

Received	2023-04-11 15:58
Peer-Review Started	2023-04-11 15:58
To Make the First Decision
Return for Revision	2023-05-19 07:16
Revised	2023-05-30 11:17
Second Decision	2023-06-08 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2023-06-09 07:38
Articles in Press	2023-06-09 07:38
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2023-07-07 10:55
Publish the Manuscript Online	2023-07-12 03:47

ISSN	1948-5190 (online)
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Category	Gastroenterology & Hepatology
Manuscript Type	Systematic Reviews
Article Title	Candy cane syndrome: A systematic review
Manuscript Source	Unsolicited Manuscript
All Author List	Ricardo Rio-Tinto, Jorge Canena and Jacques Devière
ORCID	Author(s) ORCID Number Ricardo Rio-Tinto http://orcid.org/0000-0002-4431-9908 Jorge Canena http://orcid.org/0000-0002-2539-5876
Funding Agency and Grant Number
Corresponding Author	Ricardo Rio-Tinto, MD, Consultant Physician-Scientist, Digestive Oncology Unit, Champalimaud Foundation, Avenida Brasília, Lisbon 1600, Lisbon, Portugal. ricardo.riotinto@fundacaochampalimaud.pt
Key Words	Candy cane syndrome; Blind pouch syndrome; Post-gastrectomy syndromes; Side-to-side enteral anastomosis; End-to-side enteral anastomosis
Core Tip	Enteral resections with side-to-side or end-to-end anastomosis, if a long blind end is left in place and dilates, can cause symptoms that may appear many years later. The classic designation for this clinical condition is blind pouch syndrome, although it is possible to find references under other designations, causing confusion. Candy cane syndrome (CCS) is a particular case of the blind pouch syndrome following gastrectomy or gastric bypass. CCS was first reported in a 2007 paper describing a series of patients with gastrointestinal symptoms associated with a long blind loop proximal to the gastro-jejunostomy after gastric bypass and creation of an end-to-side anastomosis to a jejunal loop. With unknown prevalence, few reports and case series have described the condition. Yet, with the increasing prevalence of obesity and number of operations being performed worldwide, surgical complications such as CCS are expected to become more frequent. Knowledge of candy cane syndrome is important to avoid delays in diagnosis and inadequate treatments. Thus, the goal of this study was to collate evidence on CCS symptoms, diagnosis, treatments, and outcomes. To the best of our knowledge, no previous literature review on this topic has been published.
Publish Date	2023-07-12 03:47
Citation	Rio-Tinto R, Canena J, Devière J. Candy cane syndrome: A systematic review. World J Gastrointest Endosc 2023; 15(7): 510-517
URL	https://www.wjgnet.com/1948-5190/full/v15/i7/510.htm
DOI	https://dx.doi.org/10.4253/wjge.v15.i7.510

Full Article (PDF)	WJGE-15-510-with-cover.pdf
Full Article (Word)	WJGE-15-510.docx
Manuscript File	85094_Auto_Edited-JLW.docx
Answering Reviewers	85094-Answering reviewers.pdf
Audio Core Tip	85094-Audio core tip.m4a
Biostatistics Review Certificate	85094-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	85094-Conflict-of-interest statement.pdf
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Non-Native Speakers of English Editing Certificate	85094-Language certificate.pdf
Peer-review Report	85094-Peer-review(s).pdf
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Scientific Editor Work List	85094-Scientific editor work list.pdf
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