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Articles Published Processes
8/14/2023 8:39:51 AM | Browse: 268 | Download: 924
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Received |
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2023-04-28 14:23 |
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Peer-Review Started |
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2023-04-28 14:25 |
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First Decision by Editorial Office Director |
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2023-05-30 19:54 |
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Return for Revision |
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2023-06-26 02:24 |
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Revised |
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2023-07-06 09:57 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2023-07-27 02:42 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2023-07-27 07:56 |
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Articles in Press |
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2023-07-27 07:56 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-08-07 02:48 |
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Publish the Manuscript Online |
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2023-08-14 08:39 |
| ISSN |
2219-2824 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, Research & Experimental |
| Manuscript Type |
Minireviews |
| Article Title |
Stem cell-like memory T cells: Role in viral infections and autoimmunity
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Meenakshi Sachdeva, Shivangi Taneja and Naresh Sachdeva |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Naresh Sachdeva, MSc, PhD, Professor, Department of Endocrinology, Post Graduate Institute of Medical Education and Research (PGIMER), Sector-12, Chandigarh 160012, India. sachdeva.naresh@pgimer.edu.in |
| Key Words |
Stem cell-like memory T cells; Viral infections; Autoimmune diseases; Effector T cells; Memory T cells |
| Core Tip |
This article discusses the contrasting roles of stem cell-like memory T (TSCM) cells during chronic viral infections and autoimmune diseases. During chronic viral infections, such as human immunodeficiency virus-1, the TSCM cells serve as reservoirs for latent viruses, which can be activated to make them susceptible to cytotoxic T cell responses. However, during acute viral infections, the TSCM cells have the ability to replenish the diminished effector T cell population. In autoimmune diseases, like type-1 diabetes, these cells contribute to the disease pathogenesis by persistent generation of autoreactive effector T cells. A better understanding of the key signaling pathways and mediators regulating TSCM cells could lead to novel approaches to target or manipulate these cells for immunotherapeutic applications. |
| Publish Date |
2023-08-14 08:39 |
| Citation |
Sachdeva M, Taneja S, Sachdeva N. Stem cell-like memory T cells: Role in viral infections and autoimmunity. World J Immunol 2023; 13(2): 11-22 |
| URL |
https://www.wjgnet.com/2219-2824/full/v13/i2/11.htm |
| DOI |
https://dx.doi.org/10.5411/wji.v13.i2.11 |
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