Publication Name	World Journal of Clinical Oncology
Manuscript ID	8547
Country	Italy

Received	2013-12-30 10:50
Peer-Review Started	2013-12-31 11:02
To Make the First Decision	2014-02-27 10:47
Return for Revision	2014-03-04 20:59
Revised	2014-04-03 21:58
Second Decision	2014-04-17 14:54
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-04-17 15:22
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-11-14 10:31
Publish the Manuscript Online	2014-12-11 14:23

ISSN	2218-4333 (online)
Open Access
Copyright
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Website	http://www.wjgnet.com

Category	Genetics & Heredity
Manuscript Type	Topic Highlights
Article Title	Polymorphisms in base excision repair genes: Breast cancer risk and individual radiosensitivity
Manuscript Source	Invited Manuscript
All Author List	Clarice Patrono, Silvia Sterpone, Antonella Testa and Renata Cozzi
Funding Agency and Grant Number
Corresponding Author	Renata Cozzi, Professor, Department of Science, University “Roma TRE”, Viale G. Marconi 446, 00146, Rome, Italy. renata.cozzi@uniroma3.it
Key Words	Breast cancer; Polymorphisms; Base excision repair; Susceptibility; Radiosensitivity
Core Tip	Single nucleotide polymorphisms (SNPs) in DNA repair genes may modulate DNA repair efficiency, influencing the development of various cancers, including breast cancer (BC). SNPs in DNA repair genes have also been studied as predictors for the risk of radiotherapy-induced side effects. We reviewed the literature on the association between SNPs in base excision repair (BER) genes and BC risk. We focused on X-ray repair cross complementing group 1, 8-oxoguanine DNA glycosylase 1, apurinic/apyrimidinic endonuclease 1 and poly (ADP-ribose) polymerase-1, which encode four important BER proteins. We also report published studies on SNPs in BER genes and individual radiosensitivity in BC patients.
Publish Date	2014-12-11 14:23
Citation	Patrono C, Sterpone S, Testa A, Cozzi R. Polymorphisms in base excision repair genes: Breast cancer risk and individual radiosensitivity. World J Clin Oncol 2014; 5(5): 874-882
URL	http://www.wjgnet.com/2218-4333/full/v5/i5/874.htm
DOI	http://dx.doi.org/10.5306/wjco.v5.i5.874

Full Article (PDF)	WJCO-5-874.pdf
Full Article (Word)	WJCO-5-874.doc
Manuscript File	8547-Review.doc
Answering Reviewers	8547-Answering reviewers.pdf
Copyright License Agreement	8547-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	8547-Language certificate.pdf
Peer-review Report	8547-Peer review(s).pdf
Scientific Editor Work List	8547-Scientific editor work list.doc