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Articles Published Processes
7/10/2023 8:58:21 AM | Browse: 240 | Download: 599
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Received |
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2023-05-04 17:05 |
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Peer-Review Started |
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2023-05-04 17:08 |
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To Make the First Decision |
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Return for Revision |
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2023-05-19 01:38 |
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Revised |
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2023-05-29 13:33 |
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Second Decision |
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2023-06-13 03:01 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-06-13 08:13 |
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Articles in Press |
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2023-06-13 08:13 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-06-27 08:36 |
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Publish the Manuscript Online |
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2023-07-10 08:58 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Oncology |
Manuscript Type |
Minireviews |
Article Title |
Progress in immunotherapy for neuroendocrine neoplasm of the digestive system
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Wei-Xuan Pan, Xin-Mu Zhang, Shao-Long Hao and Wei Han |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Wei Han, MD, Chief Doctor, Director, Director, Professor, Department of General Surgery, Beijing Luhe Hospital, No. 28 South Xinhua Road, Tongzhou District, Beijing 101100, China. dr-han1972@mail.ccmu.edu.cn |
Key Words |
Immunotherapy; PD-1 inhibitor; Neuroendocrine neoplasm; Neuroendocrine tumor; Neuroendocrine carcinoma; Gastrointestinal; Pancreatic |
Core Tip |
The application of immune checkpoint inhibitor (ICI) in neuroendocrine neoplasm (NEN) is regulated by the latest clinical practice guidelines. However, immunotherapy has achieved some breakthroughs for high-grade or advanced NENs of the digestive system, for which there is currently no effective drug therapy. In this regard, we investigated the causes of the heterogeneous efficacy of ICI in NEN with different grades, differentiation, and primary organs. This review summarizes the state-of-the-art progress and trend of clinical trials for different ICI-containing regimens in NENs of the digestive system, which will aid in the conduct of subsequent clinical trials and research of related mechanisms. |
Publish Date |
2023-07-10 08:58 |
Citation |
Pan WX, Zhang XM, Hao SL, Han W. Progress in immunotherapy for neuroendocrine neoplasm of the digestive system. World J Gastroenterol 2023; 29(26): 4174-4185 |
URL |
https://www.wjgnet.com/1007-9327/full/v29/i26/4174.htm |
DOI |
https://dx.doi.org/10.3748/wjg.v29.i26.4174 |
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