Publication Name	World Journal of Orthopedics
Manuscript ID	8566
Country	Italy

Received	2013-12-30 12:25
Peer-Review Started	2013-12-30 15:43
To Make the First Decision	2014-02-13 16:20
Return for Revision	2014-02-20 23:59
Revised	2014-03-04 07:50
Second Decision	2014-04-19 14:26
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-04-19 14:37
Articles in Press	2014-05-23 12:30
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-07-01 09:01
Publish the Manuscript Online	2014-07-19 23:48

ISSN	2218-5836 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Cell Biology
Manuscript Type	Topic Highlights
Article Title	Osteoporosis and obesity: Role of Wnt pathway in human and murine models
Manuscript Source	Invited Manuscript
All Author List	Graziana Colaianni, Giacomina Brunetti, Maria Felicia Faienza, Silvia Colucci and Maria Grano
Funding Agency and Grant Number
Corresponding Author	Graziana Colaianni, PhD, Department of Basic Medical Science, Neuroscience and Sense Organs, Section of Human Anatomy and Histology, University of Bari, Piazza Giulio Cesare 11, 70124 Bari, Italy. graziana.colaianni@libero.it
Key Words	Osteoporosis; Obesity; Bone; Fat; Wnt; Peroxisome proliferators activated receptor-γ; Dickkopf; Sclerostin
Core Tip	Here we will discuss the role of the key molecules influencing adipocytes and osteoblasts differentiation, which are peroxisome proliferators activated receptor-? and Wnts, respectively. Besides these proteins, the Wnt inhibitor molecules are also necessary to control the Wnt signalling balance from active to inactive state, in favour of osteogenesis or adipogenesis. It seems remarkably important a deepen analysis of these molecules, not only for their involvement in the regulation of the differentiation processes but also in coordinating the switch toward osteo- or adipo-genesis fate within bone marrow.
Publish Date	2014-07-19 23:48
Citation	Colaianni G, Brunetti G, Faienza MF, Colucci S, Grano M. Osteoporosis and obesity: Role of Wnt pathway in human and murine models. World J Orthop 2014; 5(3): 242-246
URL	http://www.wjgnet.com/2218-5836/full/v5/i3/242.htm
DOI	http://dx.doi.org/10.5312/wjo.v5.i3.242

Full Article (PDF)	WJO-5-242.pdf
Full Article (Word)	WJO-5-242.doc
Manuscript File	8566-Review.doc
Answering Reviewers	8566-Answering reviewers.pdf
Copyright License Agreement	8566-Copyright assignment.pdf
Peer-review Report	8566-Peer review(s).pdf
Scientific Editor Work List	8566-Scientific editor work list.doc