| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Review |
| Article Title |
Impact of gut microbiome in the development and treatment of pancreatic cancer: Newer insights
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Ayrton I Bangolo, Chinmay Trivedi, Ishan Jani, Silvanna Pender, Hirra Khalid, Budoor Alqinai, Alina Intisar, Karamvir Randhawa, Joseph Moore, Nicoleta De Deugd, Shaji Faisal, Suchith Boodgere Suresh, Parva Gopani, Vignesh K Nagesh, Tracy Proverbs-Singh and Simcha Weissman |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Ayrton I Bangolo, MBBS, MD, Doctor, Doctor, Department of Internal Medicine, Palisades Medical Center, 7600 River Road, North Bergen, NJ 07047, United States. ayrtonbangolo@yahoo.com |
| Key Words |
Pancreatic cancer; Gut microbiome; Chemotherapy; Dysbiosis; Intratumoral microbiome; Gut flora |
| Core Tip |
Pancreatic cancer (PC) remains of on the most dismal in terms of prognosis. Treatment options are limited and even after complete surgical resection, the prognosis remains poor. The gut microbiome has been incriminated in the past for the development of certain cancers. Our review found that observation to be true as well for PC. Furthermore, we also found that it plays a role in efficacy and tolerance of certain regimens used to treat PC. |
| Publish Date |
2023-06-28 07:41 |
| Citation |
Bangolo AI, Trivedi C, Jani I, Pender S, Khalid H, Alqinai B, Intisar A, Randhawa K, Moore J, De Deugd1 N, Faisal S, Suresh SB, Gopani P, Nagesh VK, Proverbs-Singh T, Weissman S. Impact of gut microbiome in the development and treatment of pancreatic cancer: Newer insights. World J Gastroenterol 2023; 29(25): 3984-3998 |
| URL |
https://www.wjgnet.com/1007-9327/full/v29/i25/3984.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v29.i25.3984 |
