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Articles Published Processes
7/19/2023 6:45:14 AM | Browse: 300 | Download: 633
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Received |
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2023-05-16 06:38 |
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Peer-Review Started |
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2023-05-16 06:41 |
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To Make the First Decision |
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Return for Revision |
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2023-05-25 03:51 |
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Revised |
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2023-06-07 03:20 |
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Second Decision |
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2023-06-21 02:58 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-06-21 09:03 |
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Articles in Press |
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2023-06-21 09:03 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-07-17 01:41 |
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Publish the Manuscript Online |
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2023-07-19 06:45 |
ISSN |
2218-4333 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Oncology |
Manuscript Type |
Review |
Article Title |
Stromal inflammation, fibrosis and cancer: An old intuition with promising potential
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Manuscript Source |
Invited Manuscript |
All Author List |
Oliver Oey, Angela Felicia Sunjaya, Yasir Khan and Andrew Redfern |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Angela Felicia Sunjaya, BMed, MD, Master's Student, Researcher, Institute of Cardiovascular Science, University College London, 62 Huntley St, London WC1E 6DD, United Kingdom. angelafelicia.s@gmail.com |
Key Words |
Inflammation; Fibrosis; Tumour microenvironment; Stroma; Cancer |
Core Tip |
Chronic inflammation and fibrosis have long been postulated to be involved in carcinogenesis via numerous mechanisms including but not limited to growth factor/cytokine-mediated cellular proliferation, apoptotic resistance, immunosuppression; and free-radical-induced oxidative deoxyribonucleic acid damage. In this review, we discuss various inflammatory and/or fibrotic conditions that have been associated with increased cancer risk, with particular emphasis on their pathophysiology. We also review various therapeutic agents and specific cancer screening that could be applicable in reducing the incidence of cancers developing from the corresponding inflammatory and/or fibrotic conditions, thereby reducing morbidity and mortality. |
Publish Date |
2023-07-19 06:45 |
Citation |
Oey O, Sunjaya AF, Khan Y, Redfern A. Stromal inflammation, fibrosis and cancer: An old intuition with promising potential. World J Clin Oncol 2023; 14(7): 230-246 |
URL |
https://www.wjgnet.com/2218-4333/full/v14/i7/230.htm |
DOI |
https://dx.doi.org/10.5306/wjco.v14.i7.230 |
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