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Articles Published Processes
11/15/2023 1:46:53 PM | Browse: 90 | Download: 341
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Received |
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2023-05-16 17:32 |
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Peer-Review Started |
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2023-05-16 17:34 |
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To Make the First Decision |
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Return for Revision |
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2023-08-07 19:07 |
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Revised |
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2023-08-15 18:04 |
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Second Decision |
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2023-09-14 02:53 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-09-14 08:55 |
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Articles in Press |
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2023-09-14 08:55 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-11-01 12:09 |
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Publish the Manuscript Online |
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2023-11-15 13:46 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Identification of necroptosis-related lncRNAs for prognosis prediction and screening of potential drugs in patients with colorectal cancer
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Zhi-Hua Chen, Yi-Lin Lin, Shao-Qin Chen and Xiao-Yu Yang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the Joint Funds for the Innovation of Science and Technology, Fujian Province |
2019Y9133 |
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| Corresponding Author |
Xiao-Yu Yang, PhD, Full Professor, School of Basic Medicine Sciences, Fujian Medical University, No. 1, Xuefu North Road, Minhou County, Fuzhou 350122, Fujian Province, China. yxyfj@163.com |
| Key Words |
Long noncoding RNA; Necroptosis; Immunotherapy; Prognosis; Colorectal cancer |
| Core Tip |
An 8-lncRNA signature significantly associated with overall survival (OS) was constructed, and its fidelity was validated in the OS, disease-specific survival and the progression-free interval, it was also validated with clinical colorectal cancer (CRC) data. The risk score which was correlated with tumor stage, lymph node metastasis and distant metastasis in CRC of the signature showed good concordance with the predicted prognosis. The high-risk group showed greater infiltration of immunosuppressive cells, but fewer infiltrating antitumor effector immune cells. We explored additional potential immune checkpoint genes and immunotherapeutic and chemotherapeutic drugs. |
| Publish Date |
2023-11-15 13:46 |
| Citation |
Chen ZH, Lin YL, Chen SQ, Yang XY. Identification of necroptosis-related lncRNAs for prognosis prediction and screening of potential drugs in patients with colorectal cancer. World J Gastrointest Oncol 2023; 15(11): 1951-1973 |
| URL |
https://www.wjgnet.com/1948-5204/full/v15/i11/1951.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v15.i11.1951 |
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