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Articles Published Processes
8/16/2023 6:59:21 AM | Browse: 116 | Download: 351
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Received |
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2023-05-19 07:53 |
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Peer-Review Started |
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2023-05-19 07:54 |
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To Make the First Decision |
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Return for Revision |
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2023-06-21 09:40 |
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Revised |
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2023-06-29 02:49 |
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Second Decision |
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2023-07-25 02:57 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-07-25 07:25 |
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Articles in Press |
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2023-07-25 07:25 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-08-03 05:38 |
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Publish the Manuscript Online |
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2023-08-16 06:59 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Mathematical & Computational Biology |
| Manuscript Type |
Meta-Analysis |
| Article Title |
Identification of key genes and biological pathways in lung adenocarcinoma by integrated bioinformatics analysis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Lin Zhang, Yuan Liu, Jian-Guo Zhuang, Jie Guo, Yan-Tao Li, Yan Dong and Gang Song |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Gang Song, MD, PhD, Chief Physician, Second Department of Respiratory Medicine, Hebei Provincial Hospital of Traditional Chinese Medicine, No. 389 Zhongshan East Road, Shijiazhuang 050000, Hebei Province, China. songgang202302@163.com |
| Key Words |
Cellular retinoic acid binding protein 2; Expression profiling data; Hub genes; Lung adenocarcinoma; Matrix metallopeptidase 12; Topoisomerase II alpha |
| Core Tip |
Lung cancer is an important cause of cancer-related death worldwide. This study conducted multiple bioinformatics analysis methods to explore potential therapeutic targets for lung adenocarcinoma (LUAD). Finally, three hub genes with high connectivity were identified, namely cellular retinoic acid binding protein 2, matrix metallopeptidase 12, and DNA topoisomerase II alpha. High expression of these genes was associated with a poor LUAD prognosis, and the genes exhibited high diagnostic value. Therefore, these genes may be biomarkers and therapeutic targets for LUAD. |
| Publish Date |
2023-08-16 06:59 |
| Citation |
Zhang L, Liu Y, Zhuang JG, Guo J, Li YT, Dong Y, Song G. Identification of key genes and biological pathways in lung adenocarcinoma by integrated bioinformatics analysis. World J Clin Cases 2023; 11(23): 5504-5518 |
| URL |
https://www.wjgnet.com/2307-8960/full/v11/i23/5504.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v11.i23.5504 |
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