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Articles Published Processes
7/27/2023 1:26:08 AM | Browse: 185 | Download: 645
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Received |
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2023-05-24 04:29 |
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Peer-Review Started |
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2023-05-24 04:31 |
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To Make the First Decision |
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Return for Revision |
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2023-06-15 09:14 |
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Revised |
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2023-06-24 13:44 |
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Second Decision |
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2023-07-07 02:39 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-07-07 06:35 |
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Articles in Press |
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2023-07-07 06:35 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-07-14 05:49 |
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Publish the Manuscript Online |
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2023-07-27 01:26 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Obstetrics & Gynecology |
| Manuscript Type |
Case Report |
| Article Title |
ADAMTS3 and FLT4 gene mutations result in congenital lymphangiectasia in newborns: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Zhu-Wei Liang and Wan-Li Gao |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| The Wu Jieping Medical Foundation Clinical Research Special Grant Fund in China |
320.6750.2022-15-9 |
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| Corresponding Author |
Wan-Li Gao, BMed, Professor, Department of Obstetrics and Gynecology, Beijing Tiantan Hospital, Capital Medical University, No. 119 South Fourth Ring West Road, Fengtai District, Beijing 100070, China. gaolisa2004@mail.ccmu.edu.cn |
| Key Words |
Congenital lymphangiectasia; ADAMTS3; FLT4; Gene mutations; Foetal pleural effusion; Case report |
| Core Tip |
Congenital lymphangiectasia is a rare disease characterized by an increased number of lymphatic vessels in the interstitium and cystic expansion of the lymphatic vessels. The genetic variations in proteins that control the development of lymphatic vessels are suggested as the pathophysiology of this disease. We analysed the case of a neonate who presented with only pleural effusion during late gestational age. However, the patient died after delivery because of the inability to establish spontaneous breathing. The autopsy indicated lymphangiectasia within systemic organs. Further, whole exome sequencing revealed rare heterozygous mutations in the lymphangiogenesis-controlling genes ADAMTS3 and FLT4. |
| Publish Date |
2023-07-27 01:26 |
| Citation |
Liang ZW, Gao WL. ADAMTS3 and FLT4 gene mutations result in congenital lymphangiectasia in newborns: A case report. World J Clin Cases 2023; 11(21): 5179-5186 |
| URL |
https://www.wjgnet.com/2307-8960/full/v11/i21/5179.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v11.i21.5179 |
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