Publication Name	World Journal of Cardiology
Manuscript ID	8597
Country	Brazil

Received	2013-12-31 09:58
Peer-Review Started	2013-12-31 10:40
To Make the First Decision	2014-02-27 10:44
Return for Revision	2014-03-04 21:04
Revised	2014-03-29 03:31
Second Decision	2014-06-03 16:17
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-06-03 16:31
Articles in Press	2014-06-03 16:52
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-06-11 16:29
Typeset the Manuscript	2014-08-28 13:59
Publish the Manuscript Online	2014-09-17 14:32

ISSN	1949-8462 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Cardiac & Cardiovascular Systems
Manuscript Type	Topic Highlights
Article Title	Interferon-γ and other inflammatory mediators in cardiomyocyte signaling during Chagas disease cardiomyopathy
Manuscript Source	Invited Manuscript
All Author List	Ludmila Rodrigues Pinto Ferreira, Amanda Farage Frade, Monique Andrade Baron, Isabela Cunha Navarro, Jorge Kalil, Christophe Chevillard and Edecio Cunha-Neto
Funding Agency and Grant Number
Corresponding Author	Edecio Cunha-Neto, MD, PhD, Researcher, Associate Professor of Medicine, Laboratory of Immunology, Heart Institute (InCor), School of Medicine, University of S?o Paulo. Av. Dr. Eneas de Carvalho Aguiar, 44 BL 2, 9° andar, 05403-001 S?o Paulo, Brazil. edecunha@usp.br
Key Words	Chagas disease; Trypanosoma cruzi; Interferon-gamma; Gene expression; Cardiomyopathy
Core Tip	Chagas disease cardiomyopathy (CCC) occurs in 30% of those infected with the protozoan Trypanosoma cruzi, endemic in Latin America. It is an inflammatory cardiomyopathy with a worse prognosis than cardiomyopathies of other etiologies. Interferon (IFN)- γ is the main cytokine produced locally and induces strong signaling in cardiomyocytes. This review focuses on the pleiotropic protective and pathogenic effects of IFN-γ on CCC.
Publish Date	2014-09-17 14:32
Citation	Ferreira LRP, Frade AF, Baron MA, Navarro IC, Kalil J, Chevillard C, Cunha-Neto E. Interferon-γ and other inflammatory mediators in cardiomyocyte signaling during Chagas disease cardiomyopathy. World J Cardiol 2014; 6(8): 782-790
URL	http://www.wjgnet.com/1949-8462/full/v6/i8/782.htm
DOI	http://dx.doi.org/10.4330/wjc.v6.i8.782

Full Article (PDF)	WJC-6-782.pdf
Full Article (Word)	WJC-6-782.doc
Manuscript File	8597-Review.doc
Answering Reviewers	8597-Answering reviewers.PDF
Copyright License Agreement	8597-Copyright assignment.pdf
Peer-review Report	8597-Peer review(s).pdf
Scientific Misconduct Check	8597-CrossCheck.jpg
Scientific Editor Work List	8597-Scientific editor work list.pdf