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9/22/2023 12:52:15 PM | Browse: 191 | Download: 423
Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 86033
Country China
Received
2023-05-30 08:03
Peer-Review Started
2023-05-30 08:05
To Make the First Decision
Return for Revision
2023-07-04 03:48
Revised
2023-07-12 09:53
Second Decision
2023-08-01 02:31
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2023-08-01 08:02
Articles in Press
2023-08-01 08:02
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2023-08-31 03:03
Publish the Manuscript Online
2023-09-22 12:52
ISSN 1948-9366 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Surgery
Manuscript Type Case Report
Article Title Dual transformation therapy for giant hepatocellular carcinoma: Two case reports and review of literature
Manuscript Source Unsolicited Manuscript
All Author List Qiang Gao, Guang-Zhi Zhu, Chuang-Ye Han, Xin-Ping Ye, Hua-Sheng Huang, Shu-Tian Mo and Tao Peng
ORCID
Author(s) ORCID Number
Guang-Zhi Zhu http://orcid.org/0000-0001-5958-7289
Xin-Ping Ye http://orcid.org/0000-0002-9200-1312
Hua-Sheng Huang http://orcid.org/0000-0003-1112-5071
Tao Peng http://orcid.org/0000-0001-6133-7078
Funding Agency and Grant Number
Corresponding Author Tao Peng, PhD, Chief Doctor, Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangxi Medical University, No. 6 Shuangyong Road, Nanning 530000, Guangxi Zhuang Autonomous Region, China. pengtaogmu@163.com
Key Words Giant hepatocellular carcinoma; Laparoscopic right portal vein ligation; hepatic arterial infusion chemotherapy; Anti-PD-1 immunotherapy; Tyrosine kinase inhibitor; Case report
Core Tip There have been many clinical studies on translational therapy for giant hepatocellular carcinoma, but simply seeking surgical transformation always carries the risk of tumor progression. There's a combination of control and transformation in oncology either immunotherapy, targeted therapy, or a combination of both. In addition, we added hepatic arterial infusion chemotherapy to seek better prognosis. In addition to the success of surgical transformation in the 2 patients reported by us, the postoperative pathology also suggested good oncology control and transformation. This treatment regimen is promising to provide more opportunities for radical hepatectomy and better prognosis for patients with large liver cancer.
Publish Date 2023-09-22 12:52
Citation Gao Q, Zhu GZ, Han CY, Ye XP, Huang HS, Mo ST, Peng T. Dual transformation therapy for giant hepatocellular carcinoma: Two case reports and review of literature. World J Gastrointest Surg 2023; 15(9): 2089-2097
URL https://www.wjgnet.com/1948-9366/full/v15/i9/2089.htm
DOI https://dx.doi.org/10.4240/wjgs.v15.i9.2089
Full Article (PDF) WJGS-15-2089-with-cover.pdf
Full Article (Word) WJGS-15-2089.docx
CARE Checklist–2016 86033-CARE-Checklist–2016-revision.pdf
Manuscript File 86033_Auto_Edited-JLW.docx
Answering Reviewers 86033-Answering reviewers.pdf
Audio Core Tip 86033-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 86033-Conflict-of-interest statement.pdf
Copyright License Agreement 86033-Copyright license agreement .pdf
Signed Consent for Treatment Form(s) or Document(s) 86033-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate 86033-Language certificate.pdf
Peer-review Report 86033-Peer-review(s).pdf
Scientific Misconduct Check 86033-Bing-Yan JP-2.png
Scientific Editor Work List 86033-Scientific editor work list.pdf
CrossCheck Report 86033-CrossCheck report.pdf