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9/25/2023 11:20:42 AM | Browse: 163 | Download: 571
Publication Name World Journal of Clinical Cases
Manuscript ID 86188
Country China
Received
2023-06-22 05:21
Peer-Review Started
2023-06-22 05:24
To Make the First Decision
Return for Revision
2023-08-08 03:53
Revised
2023-08-22 03:58
Second Decision
2023-09-04 02:53
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2023-09-04 08:37
Articles in Press
2023-09-04 08:37
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2023-09-13 09:15
Publish the Manuscript Online
2023-09-25 11:20
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Case Report
Article Title Hyperprogression after anti-programmed death-1 therapy in a patient with urothelial bladder carcinoma: A case report
Manuscript Source Unsolicited Manuscript
All Author List Hong-Yu Yang, Yu-Xuan Du, Yu-Jia Hou, Dian-Rong Lu and Peng Xue
ORCID
Author(s) ORCID Number
Hong-Yu Yang http://orcid.org/0009-0007-3913-4451
Dian-Rong Lu http://orcid.org/0009-0005-4964-256X
Peng Xue http://orcid.org/0000-0002-0798-7878
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation No. 81973640
Corresponding Author Dian-Rong Lu, Doctor, PhD, Chief Physician, Professor, Department of Oncology, Wangjing Hospital, China Academy of Chinese Medical Sciences, No. 6 Huajiadi Street, Chaoyang District, Beijing 100000, China. ludianrong@aliyun.com
Key Words Bladder urothelial carcinoma; Hyperprogression; Immunotherapy; Toripalimab; Case report
Core Tip We report a patient with bladder urothelial carcinoma (UC) who received anti- programmed death-ligand 1 agent toripalimab after surgery and chemotherapy over 12 mo had a treatment failure time less than 2 mo and showed a hyperprogression. Currently, it is still a challenge to select the patients most likely to respond to treatment with immunotherapeutic agents. For elderly patients with advanced UC, immunotherapy should be used prudently if there is no clear effective biomarker. In this case presentation, we include information on genetic alterations. With continued clinical trials and basic research, the risk factors for immunotherapy-related hyperprogressive disease will become clearer.
Publish Date 2023-09-25 11:20
Citation Yang HY, Du YX, Hou YJ, Lu DR, Xue P. Hyperprogression after anti-programmed death-1 therapy in a patient with urothelial bladder carcinoma: A case report. World J Clin Cases 2023; 11(28): 6841-6849
URL https://www.wjgnet.com/2307-8960/full/v11/i28/6841.htm
DOI https://dx.doi.org/10.12998/wjcc.v11.i28.6841
Full Article (PDF) WJCC-11-6841-with-cover.pdf
Full Article (Word) WJCC-11-6841.docx
CARE Checklist–2016 86188-CARE Checklist (2016).pdf
Manuscript File 86188_Auto_Edited-JLW.docx
Answering Reviewers 86188-Answering reviewers.pdf
Audio Core Tip 86188-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 86188-Conflict-of-interest statement.pdf
Copyright License Agreement 86188-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 86188-Grant application form(s).pdf
Signed Consent for Treatment Form(s) or Document(s) 86188-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate 86188-Language certificate.pdf
Peer-review Report 86188-Peer-review(s).pdf
Scientific Misconduct Check 86188-Bing-Chen YL-2.png
Scientific Editor Work List 86188-Scientific editor work list.pdf
CrossCheck Report 86188-CrossCheck report.pdf