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Articles Published Processes
9/25/2023 11:20:43 AM | Browse: 113 | Download: 233
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Received |
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2023-06-29 10:49 |
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Peer-Review Started |
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2023-06-29 10:51 |
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To Make the First Decision |
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Return for Revision |
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2023-08-09 08:38 |
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Revised |
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2023-08-18 13:17 |
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Second Decision |
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2023-09-06 02:43 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2023-09-06 07:56 |
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Articles in Press |
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2023-09-06 07:56 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2023-09-03 19:03 |
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Typeset the Manuscript |
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2023-09-17 09:43 |
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Publish the Manuscript Online |
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2023-09-25 11:20 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Hematology |
| Manuscript Type |
Case Report |
| Article Title |
Leukemic transformation during anti-tuberculosis treatment in aplastic anemia-paroxysmal nocturnal hemoglobinuria syndrome: A case report and review of literature
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Nuan-Nuan Xiu, Xiao-Dong Yang, Jia Xu, Bo Ju, Xiao-Yun Sun and Xi-Chen Zhao |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Xi-Chen Zhao, MD, Chief Physician, Department of Hematology, The Central Hospital of Qingdao West Coast New Area, No. 9 Huangpujiang Road, Qingdao 266555, Shandong Province, China. zhaoxichen2003@163.com |
| Key Words |
Aplastic anemia; Paroxysmal nocturnal hemoglobinuria; Acute myeloid leukemia; Tuberculosis; Leukemic transformation; Case report |
| Core Tip |
A Chinese female had a 6-year history of nonsevere aplastic anemia and a 2-year history of paroxysmal nocturnal hemoglobinuria. With aggravation of systemic inflammatory symptoms, severe pancytopenia developed, and her hemoglobinuria disappeared. Laboratory findings met the diagnostic criteria for “severe aplastic anemia.” Anti-tuberculosis treatment resulted in leukemic transformation after a short duration of hematological remission. This case study revealed that aggravated inflammatory stressors can repress normal and leukemic hematopoiesis, and relieved inflammatory stressors can facilitate penetration of neoplastic hematopoiesis, suggesting an inflammatory stress-fueled antileukemic mechanism. |
| Publish Date |
2023-09-25 11:20 |
| Citation |
Xiu NN, Yang XD, Xu J, Ju B, Sun XY, Zhao XC. Leukemic transformation during anti-tuberculosis treatment in aplastic anemia-paroxysmal nocturnal hemoglobinuria syndrome: A case report and review of literature. World J Clin Cases 2023; 11(28): 6908-6919 |
| URL |
https://www.wjgnet.com/2307-8960/full/v11/i28/6908.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v11.i28.6908 |
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