Publication Name	World Journal of Cardiology
Manuscript ID	8664
Country	Japan

Received	2014-01-02 09:59
Peer-Review Started	2014-01-02 17:12
To Make the First Decision	2014-01-16 08:18
Return for Revision	2014-01-21 19:28
Revised	2014-02-10 21:47
Second Decision	2014-08-31 16:51
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-08-31 17:02
Articles in Press	2014-08-31 17:02
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-10-27 14:58
Publish the Manuscript Online	2014-11-05 09:45

ISSN	1949-8462 (online)
Open Access
Copyright
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Website	http://www.wjgnet.com

Category	Cardiac & Cardiovascular Systems
Manuscript Type	Topic Highlights
Article Title	High-density lipoprotein and atherosclerosis: Roles of lipid transporters
Manuscript Source	Invited Manuscript
All Author List	Yoshinari Uehara and Keijiro Saku
Funding Agency and Grant Number
Corresponding Author	Yoshinari Uehara, MD, PhD, Department of Cardiology, Fukuoka University School of Medicine, 7-45-1 Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan. ueharay@fukuoka-u.ac.jp
Key Words	ATP-binding cassette transporter; ATP-binding cassette A1; ATP-binding cassette G1; Apolipoprotein A-I; High-density lipoprotein; High-density lipoprotein therapy; apoA-I mimetic peptide; Reconstitutedf high-density lipoprotein
Core Tip	The reverse cholesterol transport pathway played with high-density lipoprotein (HDL) has several potential antiatherogenic properties. Both ATP-binding cassette (ABC) A1 and ABCG1 are lipid transporters and have been involved in mediating cholesterol effluxes from cells in the presence of HDL or apoA-I, and they exerted antiatherosclerotic effects. As a therapeutic approach for increasing HDL cholesterol levels, much focus has been placed on increasing not only HDL cholesterol levels, but also HDL-biological functions. Reconstituted HDL and apoA-I mimetics have significant atheroprotective potential, as it uses lipid transporter-targeting agents, and may prove to be a novel therapeutic tool for atherosclerotic cardiovascular diseases.
Publish Date	2014-11-05 09:45
Citation	Uehara Y, Saku K. High-density lipoprotein and atherosclerosis: Roles of lipid transporters. World J Cardiol 2014; 6(10): 1049-1059
URL	http://www.wjgnet.com/1949-8462/full/v6/i10/1049.htm
DOI	http://dx.doi.org/10.4330/wjc.v6.i10.1049

Full Article (PDF)	WJC-6-1049.pdf
Full Article (Word)	WJC-6-1049.doc
Manuscript File	8664-Review.docx
Answering Reviewers	8664-Answering reviewers.pdf
Copyright License Agreement	8664-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	8664-Language certificate.pdf
Peer-review Report	8664-Peer review(s).pdf
Scientific Misconduct Check	8664-CorssCheck.jpg
Scientific Editor Work List	8664-Scientific editor work list.pdf