Publication Name	World Journal of Gastroenterology
Manuscript ID	8667
Country	Serbia

Received	2014-01-02 10:12
Peer-Review Started	2014-01-02 17:24
To Make the First Decision	2014-01-24 13:58
Return for Revision	2014-01-24 21:39
Revised	2014-02-18 00:55
Second Decision	2014-03-19 13:57
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-03-19 14:57
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-04-18 19:26
Typeset the Manuscript	2014-05-22 16:35
Publish the Manuscript Online	2014-06-06 16:55

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Case Control Study
Article Title	Role of cystatin C and renal resistive index in assessment of renal function in patients with liver cirrhosis
Manuscript Source	Unsolicited Manuscript
All Author List	Đorđe Ćulafić, Miloš Štulić, Radmila Obrenović, Danijela Miletić, Dragana Mijač, Milica Stojković, Marija Jovanović and Milica Ćulafić
Funding Agency and Grant Number	Funding Agency Grant Number Ministry of Education, Science and Technological Development, Belgrade, Republic of Serbia 175036
Corresponding Author	Milica ?ulafi?, MSc, Department of Pharmacokinetics and Clinical Pharmacy, Faculty of Pharmacy, University of Belgrade, Vojvode Stepe 450 Street, 11000 Belgrade, Serbia. milica.culafic@gmail.com
Key Words	Liver cirrhosis; Cystatin C; Renal resistive index
Core Tip	Early diagnosis of renal dysfunction is important to prevent serious complications. We conducted a study of 63 patients with liver cirrhosis and 30 healthy controls. Serum cystatin C (CysC) was measured and renal Doppler ultrasonography was performed. More patients with decreased glomerular filtration rate (GFR) were identified based on CysC GFR than on creatinine GFR. Higher renal resistive index in advanced disease by Child-Pugh and model of end stage liver disease was noticed. Renal resistive index (RRI) correlated with CysC and negatively correlated with glomerular filtration rate from serum cystatin C. Cystatin C may be a more reliable marker for liver insufficiency assessment. CysC and RRI represent sensitive indicators of renal dysfunction in liver cirrhosis.
Publish Date	2014-06-06 16:55
Citation	Ćulafić Đ, Štulić M, Obrenović R, Miletić D, Mijač D, Stojković M, Jovanović M, Ćulafić M. Role of cystatin C and renal resistive index in assessment of renal function in patients with liver cirrhosis. World J Gastroenterol 2014; 20(21): 6573-6579
URL	http://www.wjgnet.com/1007-9327/full/v20/i21/6573.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i21.6573

Full Article (PDF)	WJG-20-6573.pdf
Full Article (Word)	WJG-20-6573.doc
Manuscript File	8667-Review.doc
Answering Reviewers	8667-Answering reviewers.pdf
Copyright License Agreement	8667-Copyright Assignment.pdf
Institutional Review Board Approval Form or Document	Ethics_Committee_20140101015417.pdf
Non-Native Speakers of English Editing Certificate	8667-Language certificate.pdf
Peer-review Report	8667-Peer review(s).pdf
Scientific Editor Work List	8667-Scientific editor work list.doc