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10/12/2023 4:44:25 AM | Browse: 145 | Download: 662
Publication Name World Journal of Psychiatry
Manuscript ID 86710
Country China
Received
2023-08-16 09:26
Peer-Review Started
2023-08-16 09:26
To Make the First Decision
Return for Revision
2023-08-31 03:51
Revised
2023-09-08 09:05
Second Decision
2023-09-22 02:49
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2023-09-22 07:31
Articles in Press
2023-09-22 07:31
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2023-10-07 18:57
Publish the Manuscript Online
2023-10-12 04:44
ISSN 2220-3206 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Psychology
Manuscript Type Case Control Study
Article Title Serum neuronal pentraxin 2 is related to cognitive dysfunction and electroencephalogram slow wave/fast wave frequency ratio in epilepsy
Manuscript Source Unsolicited Manuscript
All Author List Xiao-Fen Huang, Ming-Xia Xu, Yue-Fan Chen, Yun-Qing Lin, Yuan-Xiang Lin and Feng Wang
ORCID
Author(s) ORCID Number
Xiao-Fen Huang http://orcid.org/0009-0001-2609-0791
Feng Wang http://orcid.org/0009-0003-3379-4580
Funding Agency and Grant Number
Funding Agency Grant Number
2022 Educational Research Program for Young and Middle-aged Teachers in Fujian Province (Science and Technology) JAT220107
Corresponding Author Feng Wang, MD, Doctor, Doctor, Postdoc, Professor, Department of Neurosurgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, No. 999, Huashan Road, Changle District, Fuzhou 350212, Fujian Province, China. fengwedu@163.com
Key Words Serum neuronal pentraxin 2; Cognitive dysfunction; Epilepsy; Electroencephalogram slow wave/fast wave frequency ratio; Biomarker
Core Tip Here, we found serum neuronal pentraxin 2 (NPTX2) levels were found to be significantly higher in the normal group than in the cognitive dysfunction group. Additionally, NPTX2 levels showed a positive correlation with cognitive function scores and a negative correlation with epilepsy duration and electroencephalogram (EEG) slow wave/fast wave frequency ratio values in the temporal region. Serum NPTX2 level and the EEG slow wave/fast wave frequency ratio value had good sensitivity and specificity for evaluating cognitive dysfunction. These findings suggest that serum NPTX2 could be a valuable biomarker for diagnosing cognitive impairment in patients with epilepsy, providing important insights for clinical practice.
Publish Date 2023-10-12 04:44
Citation Huang XF, Xu MX, Chen YF, Lin YQ, Lin YX, Wang F. Serum neuronal pentraxin 2 is related to cognitive dysfunction and electroencephalogram slow wave/fast wave frequency ratio in epilepsy. World J Psychiatry 2023; 13(10): 714-723
URL https://www.wjgnet.com/2220-3206/full/v13/i10/714.htm
DOI https://dx.doi.org/10.5498/wjp.v13.i10.714
Full Article (PDF) WJP-13-714-with-cover.pdf
Full Article (Word) WJP-13-714.docx
STROBE Statement 86710-STROBE statement.pdf
Manuscript File 86710_Auto_Edited-JLW.docx
Answering Reviewers 86710-Answering reviewers.pdf
Audio Core Tip 86710-Audio core tip.mp3
Biostatistics Review Certificate 86710-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 86710-Conflict-of-interest statement.pdf
Copyright License Agreement 86710-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 86710-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 86710-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 86710-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 86710-Language certificate.pdf
Peer-review Report 86710-Peer-review(s).pdf
Scientific Misconduct Check 86710-Bing-Lin C-2.png
Scientific Editor Work List 86710-Scientific editor work list.pdf
CrossCheck Report 86710-CrossCheck.png
CrossCheck Report 86710-CrossCheck report.pdf