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Articles Published Processes
1/19/2024 11:18:02 AM | Browse: 457 | Download: 644
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Received |
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2023-08-30 09:19 |
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Peer-Review Started |
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2023-08-30 09:19 |
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To Make the First Decision |
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Return for Revision |
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2023-09-13 02:36 |
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Revised |
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2023-10-11 08:16 |
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Second Decision |
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2023-11-28 23:55 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-12-05 03:50 |
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Articles in Press |
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2023-12-05 03:50 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-01-11 02:39 |
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Publish the Manuscript Online |
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2024-01-19 11:18 |
ISSN |
2220-3206 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Anesthesiology |
Manuscript Type |
Retrospective Cohort Study |
Article Title |
Effects of ulinastatin combined with dexmedetomidine on cognitive dysfunction and emergence agitation in elderly patients who underwent total hip arthroplasty
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Qi-Fan Huo, Li-Juan Zhu, Jian-Wei Guo, Yan-An Jiang and Jing Zhao |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Jing Zhao, MM, Doctor, Doctor, Department of Anesthesiology, Shaanxi Provincial People’s Hospital, No. 256 Youyi West Road, Beilin District, Xi’an 710068, Shaanxi Province, China. zhaojingsxxa@163.com |
Key Words |
Ulinastatin; Dexmedetomidine; Postoperative cognitive dysfunction; Inflammatory cytokines; Total hip arthroplasty |
Core Tip |
In this study, we found a significant difference in the score of 24 h visual analogue scale among the three groups, and the score in the dexmedetomidine (Dex)+ ulinastatin group was the lowest. Compared with the Dex and ulinastatin group, the Mini-Mental State Examination scores of the Dex + ulinastatin group were significantly increased at 1 and 7 d after the operation. Compared with the Dex and ulinastatin group, the incidence of postoperative cognitive dysfunction (POCD), the levels of serum inflammatory cytokines of the Dex + ulinastatin group were significantly decreased at 1 and 7 d after the operation. The observer’s assessment of the alertness/sedation score and Ramsay score of the Dex + ulinastatin group were significantly different from those of the Dex and ulinastatin groups on the first day after the operation. We observed that ulinastatin combined with dexmedetomidine can prevent the occurrence of POCD and the emergence of agitation in elderly patients undergoing total hip arthroplasty. |
Publish Date |
2024-01-19 11:18 |
Citation |
Huo QF, Zhu LJ, Guo JW, Jiang YA, Zhao J. Effects of ulinastatin combined with dexmedetomidine on cognitive dysfunction and emergence agitation in elderly patients who underwent total hip arthroplasty. World J Psychiatry 2024; 14(1): 26-35 |
URL |
https://www.wjgnet.com/2220-3206/full/v14/i1/26.htm |
DOI |
https://dx.doi.org/10.5498/wjp.v14.i1.26 |
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