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1/19/2024 11:18:02 AM | Browse: 367 | Download: 179
Publication Name World Journal of Psychiatry
Manuscript ID 86746
Country China
Received
2023-08-30 09:19
Peer-Review Started
2023-08-30 09:19
To Make the First Decision
Return for Revision
2023-09-13 02:36
Revised
2023-10-11 08:16
Second Decision
2023-11-28 23:55
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2023-12-05 03:50
Articles in Press
2023-12-05 03:50
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2024-01-11 02:39
Publish the Manuscript Online
2024-01-19 11:18
ISSN 2220-3206 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Anesthesiology
Manuscript Type Retrospective Cohort Study
Article Title Effects of ulinastatin combined with dexmedetomidine on cognitive dysfunction and emergence agitation in elderly patients who underwent total hip arthroplasty
Manuscript Source Unsolicited Manuscript
All Author List Qi-Fan Huo, Li-Juan Zhu, Jian-Wei Guo, Yan-An Jiang and Jing Zhao
ORCID
Author(s) ORCID Number
Jing Zhao http://orcid.org/0009-0001-2373-685X
Funding Agency and Grant Number
Corresponding Author Jing Zhao, MM, Doctor, Department of Anesthesiology, Shaanxi Provincial People’s Hospital, No. 256 Youyi West Road, Beilin District, Xi’an 710068, Shaanxi Province, China. zhaojingsxxa@163.com
Key Words Ulinastatin; Dexmedetomidine; Postoperative cognitive dysfunction; Inflammatory cytokines; Total hip arthroplasty
Core Tip In this study, we found a significant difference in the score of 24 h visual analogue scale among the three groups, and the score in the dexmedetomidine (Dex)+ ulinastatin group was the lowest. Compared with the Dex and ulinastatin group, the Mini-Mental State Examination scores of the Dex + ulinastatin group were significantly increased at 1 and 7 d after the operation. Compared with the Dex and ulinastatin group, the incidence of postoperative cognitive dysfunction (POCD), the levels of serum inflammatory cytokines of the Dex + ulinastatin group were significantly decreased at 1 and 7 d after the operation. The observer’s assessment of the alertness/sedation score and Ramsay score of the Dex + ulinastatin group were significantly different from those of the Dex and ulinastatin groups on the first day after the operation. We observed that ulinastatin combined with dexmedetomidine can prevent the occurrence of POCD and the emergence of agitation in elderly patients undergoing total hip arthroplasty.
Publish Date 2024-01-19 11:18
Citation Huo QF, Zhu LJ, Guo JW, Jiang YA, Zhao J. Effects of ulinastatin combined with dexmedetomidine on cognitive dysfunction and emergence agitation in elderly patients who underwent total hip arthroplasty. World J Psychiatry 2024; 14(1): 26-35
URL https://www.wjgnet.com/2220-3206/full/v14/i1/26.htm
DOI https://dx.doi.org/10.5498/wjp.v14.i1.26
Full Article (PDF) WJP-14-26-with-cover.pdf
Full Article (Word) WJP-14-26.docx
STROBE Statement 86746-STROBE statement.pdf
Manuscript File 86746_Auto_Edited-JLW.docx
Answering Reviewers 86746-Answering reviewers.pdf
Audio Core Tip 86746-Audio core tip.mp3
Biostatistics Review Certificate 86746-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 86746-Conflict-of-interest statement.pdf
Copyright License Agreement 86746-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 86746-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 86746-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 86746-Language certificate.pdf
Peer-review Report 86746-Peer-review(s).pdf
Scientific Misconduct Check 86746-Bing-Wang JJ-2.png
Scientific Editor Work List 86746-Scientific editor work list.pdf