Publication Name	World Journal of Gastroenterology
Manuscript ID	8675
Country	China

Received	2014-01-02 11:18
Peer-Review Started	2014-01-02 20:47
To Make the First Decision	2014-02-14 18:00
Return for Revision	2014-02-18 21:07
Revised	2014-03-04 23:09
Second Decision	2014-04-09 09:26
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-04-09 11:08
Articles in Press	2014-05-23 10:45
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-05-04 07:08
Typeset the Manuscript	2014-06-22 15:14
Publish the Manuscript Online	2014-07-03 15:30

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Randomized Controlled Trial
Article Title	ER stress and ER stress-induced apoptosis are activated in gastric SMCs in diabetic rats
Manuscript Source	Unsolicited Manuscript
All Author List	Xia Chen, Xiang-Sheng Fu, Chang-Ping Li and Hong-Xian Zhao
Funding Agency and Grant Number	Funding Agency Grant Number Department of Health, Sichuan Province, China 070267
Corresponding Author	Hong-Xian Zhao, MD, Associate Professor, Department of Histology and Embryology, Luzhou Medical College, No. 25, Taiping Street, Luzhou 646000, Sichuan Province, China. 970217858@qq.com
Key Words	Diabetic gastroparesis; Apoptosis; Endoplasmic reticulum stress; glucose-regulated protein 78 kD; Caspase-12
Core Tip	Endoplasmic reticulum stress and/or ER stress-induced apoptosis in the etiology of diabetic gastroparesis (DGP) remain unclear. This study focuses on the muscle injury caused by ER stress in rats with DGP. We found that apoptosis of gastric smooth muscle cells (SMCs) increased in diabetic rats in addition to increased expression of the ER stress marker, glucose-regulated protein 78, and the ER-specific apoptosis mediator, caspase-12. This is the first study to demonstrate that ER stress and ER stress-induced apoptosis are activated in gastric SMCs in diabetic rats.
Publish Date	2014-07-03 15:30
Citation	Chen X, Fu XS, Li CP, Zhao HX. ER stress and ER stress-induced apoptosis are activated in gastric SMCs in diabetic rats. World J Gastroenterol 2014; 20(25): 8260-8267
URL	http://www.wjgnet.com/1007-9327/full/v20/i25/8260.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i25.8260

Full Article (PDF)	WJG-20-8260.pdf
Full Article (Word)	WJG-20-8260.doc
Manuscript File	8675-Review.doc
Answering Reviewers	8675-Answering reviewers.pdf
Copyright License Agreement	8675-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	8675-Language certificate.pdf
Peer-review Report	8675-Peer review.pdf
Scientific Editor Work List	8675-Scientific editor work list.doc