| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Multi-national observational study to assess quality of life and treatment preferences in patients with Crohn’s perianal fistulas
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Chitra Karki, Amod Athavale, Vijay Abilash, Gary Hantsbarger, Parnia Geransar, Kate Lee, Slobodan Milicevic, Marko Perovic, Leanne Raven, Magdalena Sajak-Szczerba, Abigail Silber, Annabelle Yoon and Phil Tozer |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Chitra Karki, N/A, Director, Director, Global Evidence and Outcomes-Gastroenterology, Takeda Pharmaceuticals United States, Inc, 350 Massachusetts Avenue, Cambridge, MA 02139, United States. chitra.karki@takeda.com |
| Key Words |
Burden of illness; Crohn’s disease; Discrete choice experiment; Perianal fistulas; Patient-reported outcomes; Treatment preferences |
| Core Tip |
This is the largest known observational study to quantify the burden of illness associated with Crohn’s perianal fistulas (CPF) across multiple countries, utilizing a comprehensive set of outcomes including symptom burden and impacts, and treatment experience, satisfaction, and preferences. This study confirmed that the burden of illness for patients with Crohn’s disease is significantly higher for those with CPF than those without. Patients with CPF rated lower postoperative discomfort and higher healing rates as the most desirable treatment attributes. Assessing patient treatment preferences is key to helping healthcare professionals with clinical management and treatment decisions associated with CPF. |
| Publish Date |
2023-11-27 10:26 |
| Citation |
Karki C, Athavale A, Abilash V, Hantsbarger G, Geransar P, Lee K, Milicevic S, Perovic M, Raven L, Sajak-Szczerba M, Silber A, Yoon A, Tozer P. Multi-national observational study to assess quality of life and treatment preferences in patients with Crohn’s perianal fistulas. World J Gastrointest Surg 2023; 15(11): 2537-2552 |
| URL |
https://www.wjgnet.com/1948-9366/full/v15/i11/2537.htm |
| DOI |
https://dx.doi.org/10.4240/wjgs.v15.i11.2537 |
