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Articles Published Processes
12/8/2023 5:10:59 AM | Browse: 410 | Download: 1431
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Received |
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2023-07-17 02:06 |
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Peer-Review Started |
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2023-07-17 02:08 |
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First Decision by Editorial Office Director |
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2023-08-31 07:04 |
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Return for Revision |
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2023-08-31 07:04 |
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Revised |
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2023-09-18 21:03 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2023-09-28 02:44 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2023-09-28 05:50 |
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Articles in Press |
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2023-09-28 05:50 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-12-01 08:05 |
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Publish the Manuscript Online |
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2023-12-08 05:10 |
| ISSN |
2219-2808 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Pediatrics |
| Manuscript Type |
Case Control Study |
| Article Title |
Brain metabolic profile assessed by magnetic resonance spectroscopy in children with down syndrome: Relation to intelligence quotient
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Nesreen Safwat El Feil, Heba S Elmahdy, Rasha Ahmed Elmahdy, Ahmed Abd-Elbasset Aboelezz, Heba S Dawoud and Mohammed Al-Beltagi |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Mohammed Al-Beltagi, MBChB, MD, MSc, PhD, Academic Editor, Chairman, Consultant Physician-Scientist, Professor, Researcher, Department of Pediatrics, Faculty of Medicine, Tanta University, Al bahr street, Tanta 31527, Al Gharbia, Egypt. mbelrem@hotmail.com |
| Key Words |
Children; Down syndrome; Magnetic resonance spectroscopy; Metabolic profile; Intelligence quotient |
| Core Tip |
This study compared the brain metabolic profiles of children with Down syndrome (DS) using magnetic resonance spectroscopy to healthy controls. The results showed significant reductions in specific metabolic ratios (N-acetyl aspartic acid/creatine and myoinositol/creatine) in the frontal lobes of children with DS compared to controls, as well as decreases in these ratios in the temporal and occipital lobes and basal ganglia. The study also found a significant correlation between intelligence quotient (IQ) and metabolic ratios in children with DS. These findings suggest that brain metabolic profiling could be a valuable predictor of IQ in children with DS. |
| Publish Date |
2023-12-08 05:10 |
| Citation |
El Feil NS, Elmahdy HS, Elmahdy RA, Aboelezz AAE, Dawoud HS, Al-Beltagi M. Brain metabolic profile assessed by magnetic resonance spectroscopy in children with down syndrome: Relation to intelligence quotient. World J Clin Pediatr 2023; 12(5): 310-318 |
| URL |
https://www.wjgnet.com/2219-2808/full/v12/i5/310.htm |
| DOI |
https://dx.doi.org/10.5409/wjcp.v12.i5.310 |
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