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Articles Published Processes
1/11/2024 6:17:31 AM | Browse: 185 | Download: 495
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Received |
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2023-07-27 21:25 |
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Peer-Review Started |
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2023-07-27 21:27 |
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To Make the First Decision |
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Return for Revision |
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2023-09-05 20:17 |
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Revised |
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2023-09-28 11:43 |
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Second Decision |
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2023-11-01 07:38 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-11-08 18:46 |
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Articles in Press |
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2023-11-08 18:46 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2023-11-13 11:05 |
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Typeset the Manuscript |
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2024-01-04 02:17 |
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Publish the Manuscript Online |
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2024-01-11 06:17 |
ISSN |
1948-5204 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Oncology |
Manuscript Type |
Case Report |
Article Title |
Emerging role of liquid biopsy in rat sarcoma virus mutated metastatic colorectal cancer: A case report
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
João Gramaça, Isabel Gomes Fernandes, Carolina Trabulo, Joana Gonçalves, Rita Gameiro dos Santos, Adriano Baptista and Idília Pina |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
João Gramaça, MD, Doctor, Doctor, Centro Hospitalar Barreiro Montijo, Centro Hospitalar Barreiro Montijo, Avenida Movimento das Forças Armadas, Barreiro 2830-003 , Setúbal, Portugal. jpgramaca@gmail.com |
Key Words |
Metastatic colorectal cancer; Rat sarcoma virus mutational status; Liquid biopsy; Rat sarcoma virus wild type; Neo-rat sarcoma virus wild type; Anti-epidermal growth factor receptor therapy; Case report |
Core Tip |
In patients with metastatic colorectal cancer (mCRC), the treatment options are limited and proved to be affected by rat sarcoma virus (RAS) mutational status. This manuscript describes a series of 11 RAS-mutated mCRC patients who were treated with a combination of chemotherapy and bevacizumab at first line. Four patients became neo-RAS wt after first or second line treatment and were treated with cetuximab, with advantages in terms of survival and disease progression. |
Publish Date |
2024-01-11 06:17 |
Citation |
Gramaça J, Fernandes IG, Trabulo C, Gonçalves J, dos Santos RG, Baptista A, Pina I. Emerging role of liquid biopsy in rat sarcoma virus mutated metastatic colorectal cancer: A case report. World J Gastrointest Oncol 2024; 16(1): 234-243 |
URL |
https://www.wjgnet.com/1948-5204/full/v16/i1/234.htm |
DOI |
https://dx.doi.org/10.4251/wjgo.v16.i1.234 |
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