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Articles Published Processes
12/6/2023 8:08:49 AM | Browse: 142 | Download: 412
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Received |
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2023-07-27 11:01 |
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Peer-Review Started |
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2023-07-27 11:03 |
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To Make the First Decision |
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Return for Revision |
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2023-09-05 23:38 |
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Revised |
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2023-09-26 07:43 |
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Second Decision |
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2023-11-15 02:28 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-11-27 07:16 |
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Articles in Press |
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2023-11-27 07:16 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-11-28 07:06 |
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Publish the Manuscript Online |
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2023-12-06 08:08 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Infectious Diseases |
| Manuscript Type |
Review |
| Article Title |
Research progress on the relationship between Paneth cells-susceptibility genes, intestinal microecology and inflammatory bowel disease
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Qi-Ming Zhou and Lie Zheng |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Lie Zheng, PhD, Researcher, Department of Gastroenterology, Shaanxi Hospital of Traditional Chinese Medicine, No. 2 Xihuamen, Lianhu District, Xi'an 710003, Shaanxi Province, China. liezhenglielie@126.com |
| Key Words |
Susceptibility gene; Paneth cells; Intestinal microecology; Inflammatory bowel disease |
| Core Tip |
Inflammatory bowel disease (IBD) is a disorder of the immune system and intestinal microecosystem caused by environmental factors in genetically susceptible people. Paneth cells (PCs) play a central role in IBD pathogenesis, especially in Crohn's disease development, and their morphology, number and function are regulated by susceptibility genes. In the intestine, PCs participate in the formation of the stem cell microenvironment by secreting antibacterial particles and play a role in helping maintain the intestinal microecology and intestinal mucosal homeostasis. Moreover, PC proliferation and maturation depend on symbiotic flora in the intestine. This paper describes the interactions among susceptibility genes, PCs and intestinal microecology and their effects on IBD occurrence and development. |
| Publish Date |
2023-12-06 08:08 |
| Citation |
Zhou QM, Zheng L. Research progress on the relationship between Paneth cells-susceptibility genes, intestinal microecology and inflammatory bowel disease. World J Clin Cases 2023; 11(34): 8111-8125 |
| URL |
https://www.wjgnet.com/2307-8960/full/v11/i34/8111.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v11.i34.8111 |
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