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Articles Published Processes
1/19/2024 11:18:02 AM | Browse: 590 | Download: 1155
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Received |
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2023-07-31 03:48 |
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Peer-Review Started |
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2023-07-31 03:49 |
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First Decision by Editorial Office Director |
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2023-11-01 08:10 |
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Return for Revision |
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2023-11-01 08:10 |
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Revised |
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2023-11-08 08:08 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2023-11-30 23:58 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2023-12-07 03:53 |
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Articles in Press |
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2023-12-07 03:53 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-01-11 02:45 |
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Publish the Manuscript Online |
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2024-01-19 11:18 |
| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Mathematical & Computational Biology |
| Manuscript Type |
Observational Study |
| Article Title |
Des-Arg(9) bradykinin as a causal metabolite for autism spectrum disorder
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Zhong-Yu Huang, Zi-Pan Lyu, Hong-Gui Li, Hua-Zhi You, Xiang-Na Yang and Cai-Hui Cha |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| The Guangdong Basic and Applied Basic Research Foundation |
2023A1515011432 |
| The Guangzhou Science and Technology Planning Project |
2023A04J0627 |
| National Natural Science Foundation of China |
82004256 |
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| Corresponding Author |
Zhong-Yu Huang, MD, PhD, Assistant Professor, Research Fellow, Center for Medical Research on Innovation and Translation, Institute of Clinical Medicine, Guangzhou First People’s Hospital, School of Medicine, South China University of Technology, No. 1 Panfu Road, Yuexiu District, Guangzhou 510000, Guangdong Province, China. zy1717086@163.com |
| Key Words |
Des-Arg(9) bradykinin; Autism spectrum disorder; Mendelian randomization; Metabolite; Enrichment analysis |
| Core Tip |
This study employs Mendelian randomization to uncover a potential causal relationship between plasma metabolites and autism spectrum disorder (ASD), emphasizing the role of Des-Arg(9)-bradykinin in increasing the risk of ASD. The findings underscore the significance of neuroinflammation and the response to stimulus as possible mediating factors, offering new directions for the development of diagnostic and predictive biomarkers in the clinical management of ASD. |
| Publish Date |
2024-01-19 11:18 |
| Citation |
Huang ZY, Lyu ZP, Li HG, You HZ, Yang XN, Cha CH. Des-Arg(9) bradykinin as a causal metabolite for autism spectrum disorder. World J Psychiatry 2023; 2024; 14(1): 88-101 |
| URL |
https://www.wjgnet.com/2220-3206/full/v14/i1/88.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v14.i1.88 |
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